Hs02158078_cn

• Gene Symbol: DECR2
• Assay Reference Genome Location: Chr.16:412476 on build GRCh38
• Cytoband: 16p13.3

Target Gene Details

• Entrez Gene ID: 26063
• Gene Name: 2,4-dienoyl-CoA reductase 2, peroxisomal
• Gene Aliases: PDCR, SDR17C1
• Location: Chr.16:401858-412487 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 9

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
DECR2	NM_020664.3			NP_065715.1
	AJ293009.1			CAC05664.1
	AK094340.1
	AK225961.1
	AL442076.1			CAC09442.1
	BC010740.1			AAH10740.1
	BC011968.1			AAH11968.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2422427	Chr.16:10001 - 2723164 on Build GRCh38	Duplication	RNPS1 TPSB2 MAPK8IP3 TRAF7 LOC107984876 MIR662 MCRIP2 DNASE1L2 CASKIN1 HBA1 LINC00254 ZNF598 TBL3 RGS11 PRR35 PTX4 TMEM204 HS3ST6 NPW LMF1-AS1 DDX11L10 NHLRC4 PDPK1 MIR6768 JMJD8 MIR3178 LOC729652 RPL3L NME4 SNORA64 RPL23AP5 TSC2 LOC106660606 PDIA2 IGFALS RNF151 FAM173A ECI1 MPG SNORA78 SLC9A3R2 TMEM8A NDUFB10 LOC107987233 NTN3 NTHL1 MIR4717 ABCA17P NARFL BRICD5 PGP IFT140 NME3 LOC105371046 WASIR2 MLST8 AMDHD2 LOC105371049 PRR25 CRAMP1 MRPL28 ABCA3 HAGHL CCDC154 RHBDL1 PRSS27 WDR90 NPRL3 SSTR5 C16orf91 FAHD1 LOC105371047 SNORD60 EME2 LOC100134368 MIR4516 HBQ1 HAGH TSR3 LINC00235 STUB1 FAM234A MIR6859-4 METTL26 METRN MIR3180-5 PRSS29P ATP6V0C LUC7L TPSD1 FBXL16 UNKL SOX8 CACNA1H MIR940 LMF1 MSRB1 GNPTG RPUSD1 RAB26 GFER PIGQ POLR3K GNG13 TPSG1 CCDC78 MEIOB C16orf59 SNHG9 SPSB3 AXIN1 ARHGDIG MIR3677 KCTD5 LOC105371038 DECR2 SSTR5-AS1 MRPS34 MIR6767 UBE2I MIR1225 HN1L HBZ LOC101929280 TELO2 CEMP1 TPSAB1 SNORA10 SYNGR3 CCNF MIR3176 LOC105371045 NOXO1 RHOT2 TBC1D24 RHBDF1 SNHG19 MSLN MIR6511B1 HBA2 RPS2 MIR3177 RAB11FIP3 ERVK13-1 BAIAP3 WDR24 LOC105371184 MIR5587 HBM RAB40C LOC100287175 FLJ42627 CHTF18 WFIKKN1 SNRNP25 NUBP2 LOC652276 PKD1 E4F1 C1QTNF8 CLCN7 CAPN15
dgv4810n54	Chr.16:380011 - 445662 on Build GRCh38	Loss	LOC100134368 NME4 DECR2 RPL23AP5 TMEM8A RAB11FIP3
esv3637563	Chr.16:263248 - 505590 on Build GRCh38	Gain	LOC100134368 PDIA2 NME4 FAM234A DECR2 RPL23AP5 TMEM8A MRPL28 RAB11FIP3 AXIN1 ARHGDIG RGS11
nsv570956	Chr.16:376432 - 437728 on Build GRCh38	Gain	LOC100134368 NME4 DECR2 RPL23AP5 TMEM8A RAB11FIP3
nsv570954	Chr.16:342461 - 530124 on Build GRCh38	Loss	LOC100134368 LINC00235 NME4 DECR2 RPL23AP5 TMEM8A MRPL28 RAB11FIP3 AXIN1 CAPN15
nsv457303	Chr.16:383623 - 445662 on Build GRCh38	Loss	LOC100134368 NME4 DECR2 RPL23AP5 RAB11FIP3
dgv4809n54	Chr.16:322597 - 451362 on Build GRCh38	Loss	LOC100134368 NME4 DECR2 RPL23AP5 TMEM8A MRPL28 RAB11FIP3 AXIN1
dgv32n68	Chr.16:245507 - 476226 on Build GRCh38	Loss	LOC100134368 PDIA2 NME4 FAM234A DECR2 RPL23AP5 TMEM8A MRPL28 RAB11FIP3 AXIN1 ARHGDIG RGS11

More Information

Additional Information:

For this assay, SNP(s) [rs201853407] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

reductase

Gene Ontology Categories:

Process(es)

unsaturated fatty acid biosynthetic process
cellular lipid metabolic process
oxidation-reduction process

Function(s)

receptor binding
2,4-dienoyl-CoA reductase (NADPH) activity
trans-2-enoyl-CoA reductase (NADPH) activity