Hs02185381_cn

• Gene Symbol: DTX3
• Assay Reference Genome Location: Chr.12:57606889 on build GRCh38
• Cytoband: 12q13.3

Target Gene Details

• Entrez Gene ID: 196403
• Gene Name: deltex E3 ubiquitin ligase 3
• Gene Aliases: RNF154, deltex3
• Location: Chr.12:57604327-57609804 on Build GRCh38
• Assay Gene Location: Overlaps Intron 5 - Exon 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
DTX3	NM_001286245.1			NP_001273174.1
	NM_001286246.1			NP_001273175.1
	NM_178502.3			NP_848597.1
	XM_005268697.1			XP_005268754.1
	XM_005268698.1			XP_005268755.1
	XM_005268700.1			XP_005268757.1
	XM_005268703.1			XP_005268760.1
	XM_011538022.2			XP_011536324.1
	AK092085.1			BAC03801.1
	AK094385.1			BAC04344.1
	AK128752.1
	AL831941.1	2	1693	CAD38593.2
	AY225126.1			AAP57520.1
	BC114441.1
	BC114498.1
	DA684401.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv428283	Chr.12:57435950 - 57608085 on Build GRCh38	Gain	DCTN2 DDIT3 MBD6 INHBE KIF5A DTX3 MARS MIR6758 ARHGAP9 GLI1 PIP4K2C INHBC MIR616
nsv559034	Chr.12:57466149 - 57618450 on Build GRCh38	Loss	DCTN2 DDIT3 ARHGEF25 MBD6 KIF5A DTX3 MARS MIR6758 ARHGAP9 LOC101927583 GLI1 PIP4K2C MIR616
nsv482992	Chr.12:56206217 - 57706217 on Build GRCh38	Gain+Loss	COQ10A MBD6 GLS2 CNPY2 NABP2 STAT6 PTGES3 B4GALNT1 SNORD59A ARHGAP9 CS ZBTB39 APOF LOC101927583 NEMP1 INHBC MIR616 NAB2 DCTN2 DDIT3 SLC26A10 TAC3 SDR9C7 ARHGEF25 R3HDM2 MIR1228 SLC39A5 RNF41 ANKRD52 DTX3 LRP1-AS MIR6758 STAT2 PAN2 RBMS2 NACA BAZ2A RDH16 MYO1A GPR182 INHBE STAC3 SPRYD4 HBCBP SNORD59B TIMELESS OS9 IL23A NDUFA4L2 KIF5A NXPH4 SHMT2 MARS PRIM1 ATP5B GLI1 PIP4K2C MIP SNORA105C LRP1 HSD17B6

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

Notch signaling pathway
protein ubiquitination

Function(s)

protein binding
zinc ion binding
ligase activity