Hs02215082_cn

• Gene Symbol: THNSL2
• Assay Reference Genome Location: Chr.2:88175326 on build GRCh38
• Cytoband: 2p11.2

Target Gene Details

• Entrez Gene ID: 55258
• Gene Name: threonine synthase like 2
• Gene Aliases: SOFAT, THS2, TSH2
• Location: Chr.2:88170295-88186637 on Build GRCh38
• Assay Gene Location: Within Exon 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
THNSL2	NM_001244676.1	4	670	NP_001231605.1
	NM_001244678.1	2	240	NP_001231607.1
	NM_018271.4	3	508	NP_060741.3
	XM_005264400.4	4	620	XP_005264457.1
	XM_005264401.4	4	589	XP_005264458.1
	XM_005264402.3	3	2409	XP_005264459.1
	XM_005264403.4	3	2409	XP_005264460.1
	XM_005264405.4	3	2409	XP_005264462.1
	XM_006712041.3	3	2409	XP_006712104.1
	XM_006712042.3	3	2409	XP_006712105.1
	XM_006712043.2	3	2409	XP_006712106.1
	XM_006712044.3	3	2409	XP_006712107.1
	XM_011532953.2	3	2409	XP_011531255.1
	XM_011532954.2	2	2214	XP_011531256.1
	XM_011532955.2	3	354	XP_011531257.1
	AK001778.1	3	311	BAA91904.1
	AK095303.1	3	2188
	AK289486.1	3	340
	AK315831.1	2	166
	AL832746.1	1	40
	BC035315.1	3	339	AAH35315.1
	BC047758.2	1	79	AAH47758.2
	BC064423.1	4	567	AAH64423.1
	BI765911.1	3	422
	HM185274.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv61n16	Chr.2:87343737 - 90254660 on Build GRCh38	Deletion	IGKV1D-8 MIR4435-1 FOXI3 IGKV1D-13 SMYD1 KRCC1 LOC101927050 IGKV1-5 PLGLB2 LOC101928403 IGKV3D-15 IGKC LINC00152 FABP1 LOC107985911 ANKRD36BP2 LOC730268 IGKV3-20 THNSL2 LOC101928371 MIR4780 IGKV2-24 EIF2AK3 TEX37 IGKV2-29 MIR4436A RGPD2 RPIA IGK IGKV2-26
dgv6947n54	Chr.2:87815738 - 88850700 on Build GRCh38	Gain	ANKRD36BP2 THNSL2 LOC101928371 FOXI3 MIR4780 SMYD1 EIF2AK3 KRCC1 TEX37 MIR4436A RGPD2 LOC101928403 RPIA FABP1
nsv1072005	Chr.2:87360367 - 90256528 on Build GRCh38	Deletion	IGKV1D-8 MIR4435-1 FOXI3 IGKV1D-13 SMYD1 KRCC1 LOC101927050 IGKV1-5 PLGLB2 LOC101928403 IGKV3D-15 IGKC LINC00152 FABP1 LOC107985911 ANKRD36BP2 LOC730268 IGKV3-20 THNSL2 LOC101928371 MIR4780 IGKV2-24 EIF2AK3 TEX37 IGKV2-29 MIR4436A RGPD2 RPIA IGK IGKV2-26
nsv834289	Chr.2:88083076 - 88251327 on Build GRCh38	Gain	THNSL2 SMYD1 FABP1
nsv1130752	Chr.2:87360364 - 90256525 on Build GRCh38	Deletion	IGKV1D-8 MIR4435-1 FOXI3 IGKV1D-13 SMYD1 KRCC1 LOC101927050 IGKV1-5 PLGLB2 LOC101928403 IGKV3D-15 IGKC LINC00152 FABP1 LOC107985911 ANKRD36BP2 LOC730268 IGKV3-20 THNSL2 LOC101928371 MIR4780 IGKV2-24 EIF2AK3 TEX37 IGKV2-29 MIR4436A RGPD2 RPIA IGK IGKV2-26
nsv582384	Chr.2:87987149 - 88773214 on Build GRCh38	Loss	ANKRD36BP2 THNSL2 LOC101928371 FOXI3 MIR4780 SMYD1 EIF2AK3 KRCC1 TEX37 RGPD2 LOC101928403 RPIA FABP1
nsv582386	Chr.2:88035188 - 89208087 on Build GRCh38	Loss	ANKRD36BP2 IGKV3-20 THNSL2 LOC101928371 FOXI3 MIR4780 SMYD1 IGKV2-24 EIF2AK3 KRCC1 TEX37 IGKV1-5 MIR4436A LOC101928403 IGKC RPIA IGK IGKV2-26 FABP1
nsv582383	Chr.2:87915816 - 88527080 on Build GRCh38	Gain	TEX37 RGPD2 THNSL2 FOXI3 MIR4780 SMYD1 KRCC1 FABP1

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

biological_process
serine family amino acid catabolic process
threonine biosynthetic process
dephosphorylation
2-oxobutyrate biosynthetic process

Function(s)

molecular_function
threonine synthase activity
cytokine activity
pyridoxal phosphate binding
serine binding