Hs02261824_cn

• Gene Symbol: EZR
• Assay Reference Genome Location: Chr.6:158765746 on build GRCh38
• Cytoband: 6q25.3

Target Gene Details

• Entrez Gene ID: 7430
• Gene Name: ezrin
• Gene Aliases: CVIL, CVL, HEL-S-105, VIL2
• Location: Chr.6:158765741-158819424 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 14

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
EZR	NM_001111077.1			NP_001104547.1
	NM_003379.4			NP_003370.2
	XM_011536110.1			XP_011534412.1
	AI366687.1
	AK129727.1
	AL162086.1			CAB82418.1
	BC013903.2			AAH13903.1
	BC068458.1			AAH68458.1
	FJ224318.1
	X51521.1			CAA35893.1

Target Gene Details

• Entrez Gene ID: 94120
• Gene Name: synaptotagmin like 3
• Gene Aliases: SLP3
• Location: Chr.6:158644881-158766298 on Build GRCh38
• Assay Gene Location: Within Exon 21

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SYTL3	XM_005267215.4	18	3864	XP_005267272.1
	XM_005267218.4	18	3175	XP_005267275.1
	XM_005267222.4	10	2446	XP_005267279.1
	XM_006715605.3	19	3956	XP_006715668.1
	XM_006715606.3	19	3877	XP_006715669.1
	XM_006715611.3	18	3479	XP_006715674.1
	XM_011536254.2	19	3645	XP_011534556.1
	XM_011536255.2	9	2701	XP_011534557.1
	XM_017011496.1	18	4045	XP_016866985.1
	XM_017011497.1	19	3382	XP_016866986.1
	XM_017011498.1	15	3195	XP_016866987.1

More Information

• Set Membership: Intragenic, Exonic, Non-exonic, non-DGV Variation

Panther Classification:

Molecular Function -

actin or actin-binding cytoskeletal protein

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
intestinal D-glucose absorption
sphingosine-1-phosphate signaling pathway
cytoskeletal anchoring at plasma membrane
leukocyte cell-cell adhesion
axon guidance
regulation of cell shape
regulation of cell size
positive regulation of gene expression
protein kinase A signaling
gland morphogenesis
membrane to membrane docking
microvillus assembly
astral microtubule organization
actin cytoskeleton reorganization
receptor internalization
regulation of microvillus length
regulation of actin cytoskeleton organization
cellular protein complex localization
positive regulation of multicellular organism growth
cortical microtubule organization
establishment of epithelial cell apical/basal polarity
filopodium assembly
phosphatidylinositol-mediated signaling
positive regulation of protein secretion
negative regulation of T cell receptor signaling pathway
actin filament bundle assembly
establishment of centrosome localization
establishment of endothelial barrier
negative regulation of ERK1 and ERK2 cascade
cellular response to cAMP
protein localization to cell cortex
establishment of protein localization to plasma membrane
positive regulation of establishment of protein localization to plasma membrane
negative regulation of interleukin-2 secretion
regulation of NIK/NF-kappaB signaling
regulation of organelle assembly
terminal web assembly
positive regulation of protein localization to early endosome
positive regulation of cellular protein catabolic process
negative regulation of p38MAPK cascade
positive regulation of early endosome to late endosome transport
intracellular protein transport
vesicle fusion
regulation of calcium ion-dependent exocytosis
calcium ion-regulated exocytosis of neurotransmitter

Function(s)

actin binding
protein binding
microtubule binding
protein domain specific binding
protein kinase A catalytic subunit binding
protein kinase A regulatory subunit binding
S100 protein binding
poly(A) RNA binding
cell adhesion molecule binding
actin filament binding
ATPase binding
cadherin binding involved in cell-cell adhesion
calcium ion binding
calcium-dependent phospholipid binding
Rab GTPase binding
syntaxin binding
clathrin binding
neurexin family protein binding