Hs02275867_cn

• Gene Symbol: KLRB1
• Assay Reference Genome Location: Chr.12:9607791 on build GRCh38
• Cytoband: 12p13.31

Target Gene Details

• Entrez Gene ID: 3820
• Gene Name: killer cell lectin like receptor B1
• Gene Aliases: CD161, CLEC5B, NKR, NKR-P1, NKR-P1A, NKRP1A, hNKR-P1A
• Location: Chr.12:9595274-9607901 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
KLRB1	NM_002258.2	1	111	NP_002249.1
	AK292022.1	1	126
	BC113997.1	1	99	AAI13998.1
	BC114516.1	1	99	AAI14517.1
	BF432813.1	1	112
	U11276.1	1	109	AAA21605.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1051530	Chr.12:8442286 - 9951690 on Build GRCh38	Gain	KLRB1 M6PR LINC00612 LOC105369728 LOC642846 CLECL1 A2ML1 CLEC2A KLRF1 CLEC12A RIMKLB CLEC4E CLEC4D CLEC2D PZP DDX12P LOC105369649 KLRG1 LOC100506159 A2MP1 MFAP5 PHC1 LINC00987 LOC400002 CLEC2B LOC101930452 LOC728715 LOC101928030 OVOS AICDA CLEC6A LOC374443 LOC105376678 KLRF2 MIR1244-3 A2M-AS1 CD69 A2M
esv3628509	Chr.12:9603613 - 9613864 on Build GRCh38	Loss	KLRB1
nsv603	Chr.12:9605313 - 9637467 on Build GRCh38	Insertion	KLRB1 LOC374443
esv3628510	Chr.12:9604249 - 9611309 on Build GRCh38	Loss	KLRB1
esv2759878	Chr.12:9218999 - 9770933 on Build GRCh38	Gain+Loss	KLRB1 A2MP1 LINC00987 LOC101930452 LOC728715 LOC105369728 LOC101928030 LOC642846 CLECL1 OVOS LOC374443 LOC105376678 MIR1244-3 CLEC2D DDX12P CD69 LOC105369649 KLRG1
nsv428271	Chr.12:9407491 - 9678072 on Build GRCh38	Gain	LOC105376678 KLRB1 CLEC2D LOC105369728 DDX12P OVOS LOC374443

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

cell surface receptor signaling pathway
regulation of immune response

Function(s)

transmembrane signaling receptor activity
carbohydrate binding