Hs02300140_cn

• Gene Symbol: FARP2
• Assay Reference Genome Location: Chr.2:241494757 on build GRCh38
• Cytoband: 2q37.3

Target Gene Details

• Entrez Gene ID: 9855
• Gene Name: FERM, ARH/RhoGEF and pleckstrin domain protein 2
• Gene Aliases: FIR, FRG, PLEKHC3
• Location: Chr.2:241356249-241494842 on Build GRCh38
• Assay Gene Location: Within Exon 35

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
FARP2	NM_014808.3	27	3961	NP_055623.1
	XM_011512233.1	28	3946	XP_011510535.1
	XM_011512234.1	28	3871	XP_011510536.1
	XM_011512235.1	29	4204	XP_011510537.1
	XM_011512236.1	28	4000	XP_011510538.1
	XM_017005416.1	29	4161	XP_016860905.1
	XM_017005417.1	28	4140	XP_016860906.1
	XM_017005418.1	25	3778	XP_016860907.1
	AB018336.1	27	3914
	AK127510.1	6	3192
	AL122052.1	6	1326	CAB59185.1
	AW014580.1	1	101
	HY312568.1	1	115

Target Gene Details

• Entrez Gene ID: 10494
• Gene Name: serine/threonine kinase 25
• Gene Aliases: SOK1, YSK1
• Location: Chr.2:241494707-241509730 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 14

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
STK25	NM_001271977.1			NP_001258906.1
	NM_001271978.1			NP_001258907.1
	NM_001271979.1			NP_001258908.1
	NM_001271980.1			NP_001258909.1
	NM_001282305.1			NP_001269234.1
	NM_001282306.1			NP_001269235.1
	NM_001282307.1			NP_001269236.1
	NM_001282308.1			NP_001269237.1
	NM_006374.4			NP_006365.2
	HY315908.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2759120	Chr.2:241480540 - 241562243 on Build GRCh38	Loss	STK25 FARP2 BOK-AS1 BOK

More Information

• Set Membership: Intragenic, Exonic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

cell adhesion
neuron remodeling
Rac protein signal transduction
osteoclast differentiation
actin cytoskeleton reorganization
regulation of integrin activation
regulation of Rho protein signal transduction
positive regulation of GTPase activity
semaphorin-plexin signaling pathway
podosome assembly
protein phosphorylation
response to oxidative stress
establishment or maintenance of cell polarity
signal transduction
signal transduction by protein phosphorylation
positive regulation of stress-activated MAPK cascade
intrinsic apoptotic signaling pathway in response to hydrogen peroxide
response to hydrogen peroxide
protein autophosphorylation
positive regulation of axonogenesis
Golgi localization
establishment of Golgi localization
Golgi reassembly

Function(s)

Rho guanyl-nucleotide exchange factor activity
cytoskeletal protein binding
Rac guanyl-nucleotide exchange factor activity
protein kinase activity
receptor signaling protein serine/threonine kinase activity
protein binding
ATP binding
protein homodimerization activity
metal ion binding