Hs02325081_cn

• Gene Symbol: DEDD2
• Assay Reference Genome Location: Chr.19:42199229 on build GRCh38
• Cytoband: 19q13.2

Target Gene Details

• Entrez Gene ID: 162989
• Gene Name: death effector domain containing 2
• Gene Aliases: FLAME-3
• Location: Chr.19:42198593-42220152 on Build GRCh38
• Assay Gene Location: Within Exon 8

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
DEDD2	NM_001270614.1	5	1307	NP_001257543.1
	NM_001270615.1	5	1374	NP_001257544.1
	NM_133328.3	5	1389	NP_579874.1
	NR_073046.1	5	1121
	NR_073047.1	4	941
	NR_073048.1	4	1023
	NR_073049.1	5	1045
	NR_073050.1	4	1008
	NR_073051.1	5	1107
	NR_073052.1	3	882
	XM_011526569.1	7	1433	XP_011524871.1
	XM_011526571.1	6	1411	XP_011524873.1
	XM_011526572.1	6	1335	XP_011524874.1
	XM_017026402.1	7	1427	XP_016881891.1
	XM_017026403.1	7	1495	XP_016881892.1
	AK075328.1	6	1254	BAC11551.1
	AK130203.1	5	1029
	AY125488.1	5	1258	AAM95240.1
	BC013372.2	5	1250	AAH13372.2
	BC027930.1	5	1258	AAH27930.1
	BM908148.1
	CR984238.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv520239	Chr.19:41853387 - 42426852 on Build GRCh38	Loss	LOC100505622 PRR19 MIR8077 ZNF574 LIPE-AS1 CD79A ARHGEF1 POU2F2 TMEM145 RPS19 GRIK5 MEGF8 LOC101930071 GSK3A ERF LOC100505585 MIR6797 CNFN PAFAH1B3 CIC RABAC1 ATP1A3 MIR4323 DEDD2 ZNF526 LOC390937 LIPE
nsv526186	Chr.19:42172329 - 42699355 on Build GRCh38	Gain	CEACAM1 PRR19 CNFN PAFAH1B3 MIR8077 LIPE-AS1 CEACAM8 CXCL17 CIC POU2F2 TMEM145 MEGF8 LOC101930071 DEDD2 ZNF526 GSK3A ERF LIPE
nsv833833	Chr.19:42153124 - 42278970 on Build GRCh38	Loss	DEDD2 ZNF526 CIC POU2F2 GSK3A ERF
nsv522854	Chr.19:41613927 - 42426852 on Build GRCh38	Gain	LOC100505622 CEACAM3 PRR19 MIR8077 ZNF574 LIPE-AS1 CD79A ARHGEF1 POU2F2 CEACAM7 TMEM145 RPS19 GRIK5 MEGF8 LOC101930071 GSK3A ERF LOC100505585 CEACAM5 MIR6797 CNFN CEACAM6 PAFAH1B3 CIC RABAC1 DMRTC2 CEACAM4 ATP1A3 MIR4323 DEDD2 LYPD4 ZNF526 LOC390937 LIPE

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

transcription, DNA-templated
RNA processing
extrinsic apoptotic signaling pathway via death domain receptors
rRNA catabolic process
cellular homeostasis
apoptotic nuclear changes
intracellular signal transduction
negative regulation of transcription, DNA-templated
positive regulation of extrinsic apoptotic signaling pathway

Function(s)

DNA binding
protein binding
receptor signaling complex scaffold activity