Hs02365499_cn

• Gene Symbol: ACY3
• Assay Reference Genome Location: Chr.11:67642585 on build GRCh38
• Cytoband: 11q13.2

Target Gene Details

• Entrez Gene ID: 91703
• Gene Name: aminoacylase 3
• Gene Aliases: ACY-3, HCBP1
• Location: Chr.11:67642551-67650829 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 9

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ACY3	NM_080658.1			NP_542389.1
	XM_017018549.1			XP_016874038.1
	XM_017018550.1			XP_016874039.1
	XM_017018551.1			XP_016874040.1
	AY040761.1			AAK94770.1
	AY169233.1			AAN87896.1
	BC008689.1			AAH08689.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv1981n54	Chr.11:67579272 - 68049469 on Build GRCh38	Gain	MIR7113 ALDH3B1 TCIRG1 DOC2GP MIR6753 NDUFV1 C11orf72 ALDH3B2 ACY3 TBX10 NUDT8 NDUFS8 MIR4691 GSTP1 UNC93B1 LOC105369360 FAM86C2P
esv2422195	Chr.11:67466851 - 67859430 on Build GRCh38	Duplication	MIR6752 CDK2AP2 DOC2GP PITPNM1 NDUFV1 C11orf72 CABP2 ALDH3B2 ACY3 AIP TBX10 NUDT8 GSTP1 TMEM134 FAM86C2P
dgv1982n54	Chr.11:67605006 - 67666398 on Build GRCh38	Loss	TBX10 NUDT8 DOC2GP NDUFV1 C11orf72 ALDH3B2 ACY3
dgv1214n100	Chr.11:67552445 - 67996597 on Build GRCh38	Gain	TBX10 NUDT8 DOC2GP NDUFV1 GSTP1 UNC93B1 C11orf72 LOC105369360 ALDH3B2 FAM86C2P ACY3
nsv555273	Chr.11:67628243 - 67666398 on Build GRCh38	Loss	TBX10 NUDT8 ALDH3B2 ACY3
nsv951023	Chr.11:67608030 - 67649929 on Build GRCh38	Deletion	TBX10 NUDT8 DOC2GP NDUFV1 ACY3
nsv468606	Chr.11:67585218 - 68049469 on Build GRCh38	Gain	MIR7113 ALDH3B1 TCIRG1 DOC2GP MIR6753 NDUFV1 C11orf72 ALDH3B2 ACY3 TBX10 NUDT8 NDUFS8 MIR4691 GSTP1 UNC93B1 LOC105369360 FAM86C2P

More Information

Additional Information:

For this assay, SNP(s) [rs115044142] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

xenobiotic metabolic process
biological_process
viral process

Function(s)

molecular_function
aminoacylase activity
protein binding
hydrolase activity, acting on ester bonds
identical protein binding
metal ion binding