Hs02400487_cn

• Gene Symbol: PRH1
• Assay Reference Genome Location: Chr.12:10986036 on build GRCh38
• Cytoband: 12p13.2

Target Gene Details

• Entrez Gene ID: 5554
• Gene Name: proline rich protein HaeIII subfamily 1
• Gene Aliases: Db-s, PA, PIF-S, PRH2, Pr1/Pr2
• Location: Chr.12:10880961-11171623 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PRH1	NM_001291314.1			NP_001278243.1
	NM_001291315.1			NP_001278244.1
	NR_133575.1
	AB593028.1
	AB593029.1
	BI772091.1
	BM476484.1
	BU543118.1

Target Gene Details

• Entrez Gene ID: 100533464
• Gene Name: PRH1-PRR4 readthrough
• Gene Aliases: PRH1
• Location: Chr.12:10845849-11171625 on Build GRCh38
• Assay Gene Location: Within Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PRH1-PRR4	NR_037918.2
	AB593030.1

Target Gene Details

• Entrez Gene ID: 259296
• Gene Name: taste 2 receptor member 50
• Gene Aliases: T2R50, T2R51, TAS2R51
• Location: Chr.12:10985913-10986912 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TAS2R50	NM_176890.2	1	877	NP_795371.2
	BC112100.1	1	877	AAI12101.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv973026	Chr.12:10986051 - 10987485 on Build GRCh38	Duplication	TAS2R50 PRH1 PRH1-PRR4 PRH1-TAS2R14
dgv251e214	Chr.12:10984454 - 10989296 on Build GRCh38	Loss	TAS2R50 PRH1 PRH1-PRR4 PRH1-TAS2R14
nsv832330	Chr.12:10925079 - 11054358 on Build GRCh38	Gain	TAS2R19 TAS2R50 PRH2 PRH1 PRH1-PRR4 PRH1-TAS2R14 TAS2R31 TAS2R14 TAS2R20
esv3628555	Chr.12:10984460 - 10989296 on Build GRCh38	Gain	TAS2R50 PRH1 PRH1-PRR4 PRH1-TAS2R14
esv2759879	Chr.12:10817021 - 11561987 on Build GRCh38	Loss	TAS2R43 PRH1 PRH1-PRR4 PRH1-TAS2R14 TAS2R30 TAS2R13 TAS2R10 PRB2 TAS2R31 PRB4 TAS2R42 TAS2R14 TAS2R20 LINC01252 PRB1 TAS2R19 SMIM10L1 TAS2R50 PRH2 TAS2R46 PRR4 PRB3
nsv1038277	Chr.12:10908379 - 11351157 on Build GRCh38	Loss	TAS2R43 PRH1 PRH1-PRR4 PRH1-TAS2R14 TAS2R30 TAS2R13 TAS2R31 PRB4 TAS2R42 TAS2R14 TAS2R20 TAS2R19 SMIM10L1 TAS2R50 PRH2 TAS2R46 PRB3
esv2745546	Chr.12:10980833 - 11078852 on Build GRCh38	Deletion	TAS2R19 TAS2R50 PRH1 PRH1-PRR4 PRH1-TAS2R14 TAS2R46 TAS2R31 TAS2R20
nsv428272	Chr.12:10917246 - 11561987 on Build GRCh38	Gain+Loss	TAS2R43 PRH1 PRH1-PRR4 PRH1-TAS2R14 TAS2R30 PRB2 TAS2R31 PRB4 TAS2R42 TAS2R14 TAS2R20 LINC01252 PRB1 TAS2R19 SMIM10L1 TAS2R50 PRH2 TAS2R46 PRB3

More Information

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

antimicrobial response protein, transmembrane signal receptor

Gene Ontology Categories:

Process(es)

detection of chemical stimulus involved in sensory perception of bitter taste
G-protein coupled receptor signaling pathway

Function(s)

protein binding
G-protein coupled receptor activity
bitter taste receptor activity