Hs02406226_cn

• Gene Symbol: AKIRIN2
• Assay Reference Genome Location: Chr.6:87675575 on build GRCh38
• Cytoband: 6q15

Target Gene Details

• Entrez Gene ID: 55122
• Gene Name: akirin 2
• Gene Aliases: C6orf166, FBI1, dJ486L4.2
• Location: Chr.6:87674860-87702267 on Build GRCh38
• Assay Gene Location: Overlaps Intron 4 - Exon 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
AKIRIN2	NM_018064.3			NP_060534.1
	AK222701.1			BAD96421.1
	BC000764.2			AAH00764.1
	BC003042.1			AAH03042.1
	BC005051.1			AAH05051.1

Target Gene Details

• Entrez Gene ID: 23595
• Gene Name: origin recognition complex subunit 3
• Gene Aliases: LAT, LATHEO, ORC3L
• Location: Chr.6:87590067-87677824 on Build GRCh38
• Assay Gene Location: Within Intron 23

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ORC3	XM_017010632.1			XP_016866121.1
	XM_017010633.1			XP_016866122.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv6085n100	Chr.6:87443361 - 87700332 on Build GRCh38	Gain	ORC3 RARS2 SLC35A1 CFAP206 AKIRIN2
esv2759454	Chr.6:87649270 - 87731755 on Build GRCh38	Loss	ORC3 AKIRIN2

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

DNA metabolism protein, nucleic acid metabolism protein, replication origin binding protein

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
positive regulation of cell proliferation
embryo development
positive regulation of endopeptidase activity
response to lipopolysaccharide
positive regulation of interleukin-6 production
innate immune response
positive regulation of transcription from RNA polymerase II promoter
G1/S transition of mitotic cell cycle
DNA replication
pre-replicative complex assembly involved in nuclear cell cycle DNA replication
DNA replication initiation
neural precursor cell proliferation

Function(s)

enzyme binding
DNA replication origin binding
protein binding