Hs02408123_cn

• Gene Symbol: UBE2C
• Assay Reference Genome Location: Chr.20:45812653 on build GRCh38
• Cytoband: 20q13.12

Target Gene Details

• Entrez Gene ID: 11065
• Gene Name: ubiquitin conjugating enzyme E2 C
• Gene Aliases: UBCH10, dJ447F3.2
• Location: Chr.20:45812576-45816957 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
UBE2C	NM_001281741.1	1	78	NP_001268670.1
	NM_001281742.1	1	78	NP_001268671.1
	NM_007019.3	1	78	NP_008950.1
	NM_181799.2	1	78	NP_861515.1
	NM_181800.2	1	78	NP_861516.1
	NR_104036.1	1	78
	NR_104037.1	1	78
	AK311949.1
	BC007656.2			AAH07656.1
	BC016292.1			AAH16292.1
	BC050736.1			AAH50736.1
	BM556795.1
	BM747513.1
	BU169315.1
	BU171488.1
	BU844974.1
	CB143441.1
	CK904708.1
	CN354813.1
	CN354815.1
	DB062573.1	1	78
	U73379.1			AAB53362.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv833990	Chr.20:45771510 - 45946844 on Build GRCh38	Loss	SPATA25 UBE2C PCIF1 SNX21 LOC107985388 ZSWIM1 CTSA PLTP ZSWIM3 NEURL2 TNNC2 ACOT8 DNTTIP1 WFDC3
nsv586132	Chr.20:45785138 - 45842587 on Build GRCh38	Loss	TNNC2 ACOT8 DNTTIP1 UBE2C SNX21 WFDC3

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

ubiquitin-dependent protein catabolic process
negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation
exit from mitosis
free ubiquitin chain polymerization
protein ubiquitination
regulation of mitotic metaphase/anaphase transition
anaphase-promoting complex-dependent catabolic process
positive regulation of exit from mitosis
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
cell division
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
protein K48-linked ubiquitination
protein K11-linked ubiquitination
positive regulation of ubiquitin protein ligase activity

Function(s)

ubiquitin-protein transferase activity
protein binding
ATP binding
ubiquitin protein ligase binding
ubiquitin protein ligase activity
ubiquitin conjugating enzyme activity