Hs02426877_cn

• Gene Symbol: PAPOLB
• Assay Reference Genome Location: Chr.7:4860668 on build GRCh38
• Cytoband: 7p22.1

Target Gene Details

• Entrez Gene ID: 56903
• Gene Name: poly(A) polymerase beta
• Gene Aliases: PAPT, TPAP
• Location: Chr.7:4857738-4861994 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PAPOLB	NM_020144.4	1	1327	NP_064529.4
	AF218840.1	1	1248	AAF81013.1
	AK312788.1	1	1358
	BC036653.2	1	1327	AAH36653.2

Target Gene Details

• Entrez Gene ID: 55698
• Gene Name: Rap associating with DIL domain
• Gene Aliases: RASIP2
• Location: Chr.7:4799109-4883704 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
RADIL	NM_018059.4			NP_060529.4
	AB058752.1
	AK294745.1
	BC117317.1
	BC126311.1
	BC143526.1
	EF560723.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv605980	Chr.7:4836426 - 4963742 on Build GRCh38	Loss	PAPOLB RADIL MMD2
nsv605979	Chr.7:4814961 - 4904883 on Build GRCh38	Loss	PAPOLB RADIL MMD2
esv3611950	Chr.7:4828936 - 4874508 on Build GRCh38	Loss	PAPOLB RADIL
nsv1029123	Chr.7:4782103 - 4879646 on Build GRCh38	Loss	PAPOLB AP5Z1 RADIL MIR4656
dgv6238n100	Chr.7:4810816 - 5030133 on Build GRCh38	Loss	RNF216P1 PAPOLB RADIL MMD2
nsv528748	Chr.7:4780950 - 4971362 on Build GRCh38	Loss	PAPOLB AP5Z1 RADIL MIR4656 MMD2
nsv8033	Chr.7:4762656 - 5046966 on Build GRCh38	Loss	RNF216P1 PAPOLB FOXK1 AP5Z1 RBAK-RBAKDN RBAK RADIL MIR4656 MMD2
nsv823994	Chr.7:4752754 - 4888697 on Build GRCh38	Gain	PAPOLB FOXK1 AP5Z1 RADIL MIR4656

More Information

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

mRNA polyadenylation factor

Gene Ontology Categories:

Process(es)

mRNA polyadenylation
signal transduction
multicellular organism development
substrate adhesion-dependent cell spreading

Function(s)

RNA binding
polynucleotide adenylyltransferase activity
ATP binding
metal ion binding
protein binding