Hs02513677_cn

• Gene Symbol: E2F4
• Assay Reference Genome Location: Chr.16:67194384 on build GRCh38
• Cytoband: 16q22.1

Target Gene Details

• Entrez Gene ID: 1874
• Gene Name: E2F transcription factor 4
• Gene Aliases: E2F-4
• Location: Chr.16:67192165-67198918 on Build GRCh38
• Assay Gene Location: Overlaps Intron 4 - Exon 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
E2F4	NM_001950.3			NP_001941.2
	AB451292.1
	AB451425.1
	BC033180.1			AAH33180.1
	S75174.1			AAB32597.1
	U15641.1			AAC50119.1
	X86096.1			CAA60050.2

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv522852	Chr.16:67153308 - 68071571 on Build GRCh38	Gain	AGRP CTRL LOC100131303 KIAA0895L ATP6V0D1 FAM65A DDX28 FHOD1 DPEP3 LOC107984813 ELMO3 TMEM208 RANBP10 THAP11 LRRC36 HSD11B2 SLC12A4 KCTD19 DUS2 PARD6A LRRC29 TPPP3 ZDHHC1 TRADD PSMB10 EDC4 FBXL8 SLC9A5 EXOC3L1 MIR328 GFOD2 TSNAXIP1 NOL3 PSKH1 CARMIL2 ENKD1 LOC105369155 DPEP2 C16orf86 NRN1L NUTF2 CTCF LCAT ACD LOC100505942 E2F4 HSF4 CENPT PLEKHG4
nsv827707	Chr.16:67148355 - 67289296 on Build GRCh38	Loss	LOC105369155 LRRC29 TRADD KIAA0895L C16orf70 FBXL8 SLC9A5 B3GNT9 ELMO3 EXOC3L1 TMEM208 MIR328 E2F4 FHOD1 HSF4 NOL3 PLEKHG4
nsv952044	Chr.16:67141198 - 67244397 on Build GRCh38	Deletion	LOC105369155 LRRC29 TRADD KIAA0895L C16orf70 FBXL8 B3GNT9 ELMO3 EXOC3L1 TMEM208 MIR328 E2F4 FHOD1 HSF4 NOL3
nsv1160429	Chr.16:67161549 - 67220197 on Build GRCh38	Deletion	ELMO3 EXOC3L1 LOC105369155 MIR328 LRRC29 E2F4 KIAA0895L HSF4 FBXL8 NOL3
nsv457513	Chr.16:67181417 - 67282697 on Build GRCh38	Loss	ELMO3 EXOC3L1 TMEM208 LOC105369155 MIR328 LRRC29 E2F4 FHOD1 KIAA0895L PLEKHG4 SLC9A5
nsv524492	Chr.16:67174030 - 67294550 on Build GRCh38	Loss	LOC105369155 LRRC29 KIAA0895L SLC9A5 ELMO3 EXOC3L1 TMEM208 MIR328 E2F4 FHOD1 KCTD19 NOL3 PLEKHG4
nsv524363	Chr.16:67136529 - 68071571 on Build GRCh38	Loss	AGRP CTRL LOC100131303 KIAA0895L ATP6V0D1 FAM65A DDX28 FHOD1 DPEP3 LOC107984813 ELMO3 TMEM208 RANBP10 THAP11 LRRC36 HSD11B2 SLC12A4 KCTD19 DUS2 PARD6A LRRC29 TPPP3 ZDHHC1 TRADD PSMB10 EDC4 FBXL8 SLC9A5 B3GNT9 EXOC3L1 MIR328 GFOD2 TSNAXIP1 NOL3 PSKH1 CARMIL2 ENKD1 LOC105369155 DPEP2 C16orf86 NRN1L NUTF2 C16orf70 CTCF LCAT ACD LOC100505942 E2F4 HSF4 CENPT PLEKHG4

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

RNA metabolism protein, nucleic acid metabolism protein, general transcription factor

Gene Ontology Categories:

Process(es)

regulation of transcription involved in G1/S transition of mitotic cell cycle
epithelial cell development
transcription from RNA polymerase II promoter
cell volume homeostasis
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
blood circulation
organ morphogenesis
regulation of cell proliferation
motile cilium assembly
positive regulation of transcription from RNA polymerase II promoter
centriole assembly
multi-ciliated epithelial cell differentiation

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
transcription factor binding
protein domain specific binding
promoter-specific chromatin binding