Hs02515487_cn

• Gene Symbol: GNB4
• Assay Reference Genome Location: Chr.3:179400594 on build GRCh38
• Cytoband: 3q26.33

Target Gene Details

• Entrez Gene ID: 59345
• Gene Name: G protein subunit beta 4
• Gene Aliases: CMTD1F
• Location: Chr.3:179396088-179451583 on Build GRCh38
• Assay Gene Location: Within Exon 12

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GNB4	NM_021629.3	10	1922	NP_067642.1
	XM_005247692.2	10	1843	XP_005247749.1
	XM_006713721.2	10	1853	XP_006713784.1
	AK001890.1	10	1922
	AK022599.1	1	616

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv4139	Chr.3:179384796 - 179418003 on Build GRCh38	Insertion	MFN1 GNB4
nsv829806	Chr.3:179234575 - 179436585 on Build GRCh38	Gain	MFN1 PIK3CA KCNMB3 GNB4 ZNF639
dgv4999n100	Chr.3:179227018 - 179528391 on Build GRCh38	Gain	MFN1 PIK3CA KCNMB3 GNB4 ZNF639
nsv592650	Chr.3:179250846 - 179534475 on Build GRCh38	Gain	MFN1 KCNMB3 GNB4 ZNF639

More Information

Additional Information:

For this assay, SNP(s) [rs73045155] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

heterotrimeric G-protein

Gene Ontology Categories:

Process(es)

protein folding
signal transduction
substantia nigra development
cellular response to glucagon stimulus

Function(s)

signal transducer activity
protein complex binding