Hs02548937_cn

• Gene Symbol: PDK4
• Assay Reference Genome Location: Chr.7:95589700 on build GRCh38
• Cytoband: 7q21.3

Target Gene Details

• Entrez Gene ID: 5166
• Gene Name: pyruvate dehydrogenase kinase 4
• Gene Aliases: -
• Location: Chr.7:95583497-95596613 on Build GRCh38
• Assay Gene Location: Overlaps Intron 6 - Exon 7

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PDK4	NM_002612.3			NP_002603.1
	AK096428.1
	AK098151.1
	AK223328.1			BAD97048.1
	AK312424.1
	BC040239.1			AAH40239.1
	U54617.1			AAC50669.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1023193	Chr.7:93602376 - 95828660 on Build GRCh38	Gain	PEG10 PON2 TFPI2 PON3 MIR4652 COL1A2 BET1 SGCE PPP1R9A LOC105375401 GNGT1 PDK4 ASB4 LOC105375405 PON1 DYNC1I1 GNG11 CASD1

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

positive regulation of defense response to virus by host
glucose metabolic process
protein phosphorylation
regulation of pH
insulin receptor signaling pathway
cellular response to starvation
regulation of acetyl-CoA biosynthetic process from pyruvate
regulation of cellular ketone metabolic process
regulation of glucose metabolic process
regulation of fatty acid biosynthetic process
glucose homeostasis
response to starvation
regulation of bone resorption
regulation of fatty acid oxidation
cellular response to fatty acid
reactive oxygen species metabolic process
xenophagy
negative regulation of anoikis

Function(s)

protein kinase activity
pyruvate dehydrogenase (acetyl-transferring) kinase activity
ATP binding