Hs02552127_cn

• Gene Symbol: NFS1
• Assay Reference Genome Location: Chr.20:35669293 on build GRCh38
• Cytoband: 20q11.22

Target Gene Details

• Entrez Gene ID: 9054
• Gene Name: NFS1 cysteine desulfurase
• Gene Aliases: HUSSY-08, IscS, NIFS
• Location: Chr.20:35668688-35699365 on Build GRCh38
• Assay Gene Location: Within Exon 14

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NFS1	NM_001198989.1	12	1627	NP_001185918.1
	NM_021100.4	13	1780	NP_066923.3
	NR_037570.2	14	1902
	AF097025.2	13	1766	AAD09187.2
	AJ010952.1	9	1288	CAA09424.1
	AK001265.1	13	1765
	AK001470.1	13	1776
	AK056242.1	13	2051
	AK091049.1	5	2322
	AK223239.1	13	1766	BAD96959.1
	AK297969.1	14	1889
	BC065560.1	13	1752	AAH65560.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv526188	Chr.20:35576541 - 36019079 on Build GRCh38	Gain	RBM39 ROMO1 FER1L4 CPNE1 NFS1 SPAG4 SCAND1 CNBD2 PHF20 RBM12

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

lyase, metabolite interconversion enzyme

Gene Ontology Categories:

Process(es)

sulfur amino acid metabolic process
protein complex assembly
Mo-molybdopterin cofactor biosynthetic process
iron incorporation into metallo-sulfur cluster
molybdopterin cofactor biosynthetic process
small molecule metabolic process
[2Fe-2S] cluster assembly

Function(s)

protein binding
pyridoxal phosphate binding
cysteine desulfurase activity
protein homodimerization activity
metal ion binding
iron-sulfur cluster binding