Hs02552257_cn

• Gene Symbol: FAM175A
• Assay Reference Genome Location: Chr.4:83462381 on build GRCh38
• Cytoband: 4q21.23

Target Gene Details

• Entrez Gene ID: 84142
• Gene Name: family with sequence similarity 175 member A
• Gene Aliases: ABRA1, CCDC98
• Location: Chr.4:83459515-83485181 on Build GRCh38
• Assay Gene Location: Within Exon 10

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
FAM175A	NM_139076.2	9	1383	NP_620775.2
	XM_005263280.4	10	1516	XP_005263337.1
	XM_017008694.1	8	1289	XP_016864183.1
	AK021582.1	4	1591
	AK022704.1	9	1369	BAB14189.1
	AK023676.1	8	1283	BAB14635.1
	AY358576.1	9	1334	AAQ88939.1
	BC039573.1	9	1330	AAH39573.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3893971	Chr.4:83096792 - 83493129 on Build GRCh38	Gain	HELQ FAM175A HPSE PLAC8 COQ2 MRPS18C
esv3601197	Chr.4:83448066 - 83468701 on Build GRCh38	Loss	HELQ FAM175A MRPS18C
esv3601196	Chr.4:83419958 - 83470239 on Build GRCh38	Loss	HELQ FAM175A MRPS18C
nsv829994	Chr.4:83445146 - 83637163 on Build GRCh38	Loss	HELQ FAM175A GPAT3 MRPS18C

More Information

Additional Information:

For this assay, SNP(s) [rs76266580] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

double-strand break repair
double-strand break repair via nonhomologous end joining
response to ionizing radiation
covalent chromatin modification
G2 DNA damage checkpoint
positive regulation of DNA repair

Function(s)

protein binding
polyubiquitin binding