Hs02556097_cn

• Gene Symbol: TRADD
• Assay Reference Genome Location: Chr.16:67156642 on build GRCh38
• Cytoband: 16q22.1

Target Gene Details

• Entrez Gene ID: 8717
• Gene Name: TNFRSF1A associated via death domain
• Gene Aliases: Hs.89862
• Location: Chr.16:67154185-67159909 on Build GRCh38
• Assay Gene Location: Overlaps Intron 2 - Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TRADD	NM_001323552.1			NP_001310481.1
	NM_003789.3			NP_003780.1
	XM_005256213.3			XP_005256270.1
	XM_017023815.1			XP_016879304.1
	AK301593.1
	AK315654.1
	BC004491.2			AAH04491.1
	BG717460.1
	BT006934.1			AAP35580.1
	DA353575.1
	L41690.1			AAA98482.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv522852	Chr.16:67153308 - 68071571 on Build GRCh38	Gain	CARMIL2 C16orf86 DDX28 HSD11B2 ACD DUS2 TRADD THAP11 LCAT FBXL8 ATP6V0D1 KIAA0895L FHOD1 PSKH1 TPPP3 NOL3 NRN1L ELMO3 CTRL DPEP3 LRRC36 HSF4 CTCF LOC105369155 FAM65A DPEP2 MIR328 LOC107984813 LOC100505942 GFOD2 EXOC3L1 TMEM208 CENPT PARD6A SLC9A5 KCTD19 NUTF2 LOC100131303 E2F4 AGRP EDC4 LRRC29 ENKD1 ZDHHC1 SLC12A4 TSNAXIP1 PSMB10 RANBP10 PLEKHG4
nsv827707	Chr.16:67148355 - 67289296 on Build GRCh38	Loss	E2F4 LOC105369155 B3GNT9 LRRC29 NOL3 MIR328 ELMO3 TRADD FBXL8 EXOC3L1 KIAA0895L TMEM208 HSF4 PLEKHG4 SLC9A5 FHOD1 C16orf70
nsv952044	Chr.16:67141198 - 67244397 on Build GRCh38	Deletion	E2F4 LOC105369155 B3GNT9 LRRC29 NOL3 MIR328 ELMO3 TRADD FBXL8 EXOC3L1 KIAA0895L TMEM208 HSF4 FHOD1 C16orf70
nsv524363	Chr.16:67136529 - 68071571 on Build GRCh38	Loss	CARMIL2 C16orf86 DDX28 HSD11B2 ACD DUS2 TRADD THAP11 LCAT FBXL8 ATP6V0D1 KIAA0895L FHOD1 PSKH1 TPPP3 NOL3 NRN1L ELMO3 CTRL DPEP3 LRRC36 HSF4 CTCF LOC105369155 FAM65A B3GNT9 DPEP2 MIR328 LOC107984813 LOC100505942 GFOD2 EXOC3L1 TMEM208 CENPT PARD6A SLC9A5 KCTD19 NUTF2 LOC100131303 E2F4 AGRP EDC4 LRRC29 ENKD1 ZDHHC1 SLC12A4 TSNAXIP1 PSMB10 RANBP10 PLEKHG4 C16orf70

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
signal transduction
I-kappaB kinase/NF-kappaB signaling
extrinsic apoptotic signaling pathway via death domain receptors
regulation of tumor necrosis factor-mediated signaling pathway
regulation of necrotic cell death
tumor necrosis factor-mediated signaling pathway
positive regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of NF-kappaB transcription factor activity
protein heterooligomerization
positive regulation of hair follicle development
death-inducing signaling complex assembly
extrinsic apoptotic signaling pathway
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

Function(s)

signal transducer activity
tumor necrosis factor receptor binding
protein binding
kinase binding
protein complex binding
identical protein binding
binding, bridging
death domain binding