Hs02568452_cn

• Gene Symbol: PLOD2
• Assay Reference Genome Location: Chr.3:146070001 on build GRCh38
• Cytoband: 3q24

Target Gene Details

• Entrez Gene ID: 5352
• Gene Name: procollagen-lysine,2-oxoglutarate 5-dioxygenase 2
• Gene Aliases: BRKS2, LH2, TLH
• Location: Chr.3:146069436-146161495 on Build GRCh38
• Assay Gene Location: Within Exon 22

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PLOD2	NM_000935.2	19	3436	NP_000926.2
	NM_182943.2	20	3499	NP_891988.1
	XM_005247535.3	21	3056	XP_005247592.1
	XM_017006625.1	21	3010	XP_016862114.1
	AB209879.1	19	3108	BAD93116.1
	AK130098.1	1	281
	AL832238.1	9	1658
	BC016834.1	6	1349	AAH16834.1
	BC037169.1	20	3170	AAH37169.1
	U84573.1	19	2930	AAB58363.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv525829	Chr.3:145896530 - 146145992 on Build GRCh38	Loss	PLOD2
nsv4046	Chr.3:145975462 - 146162402 on Build GRCh38	Deletion	PLOD2

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

protein modifying enzyme

Gene Ontology Categories:

Process(es)

response to hypoxia
cellular protein modification process
cellular response to hormone stimulus
oxidation-reduction process
mitophagy in response to mitochondrial depolarization

Function(s)

iron ion binding
procollagen-lysine 5-dioxygenase activity
L-ascorbic acid binding