Hs02580448_cn

• Gene Symbol: TTK
• Assay Reference Genome Location: Chr.6:80013295 on build GRCh38
• Cytoband: 6q14.1

Target Gene Details

• Entrez Gene ID: 7272
• Gene Name: TTK protein kinase
• Gene Aliases: CT96, ESK, MPH1, MPS1, MPS1L1, PYT
• Location: Chr.6:80004147-80043577 on Build GRCh38
• Assay Gene Location: Overlaps Intron 9 - Exon 10

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TTK	NM_001166691.1			NP_001160163.1
	NM_003318.4			NP_003309.2
	XM_011536099.2			XP_011534401.1
	XM_011536100.2			XP_011534402.1
	XM_017011242.1			XP_016866731.1
	AK095599.1
	AK292460.1
	AK315696.1
	AX775733.1			CAE11566.1
	BC000633.2			AAH00633.1
	BC032858.2			AAH32858.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv5370	Chr.6:80005634 - 80042023 on Build GRCh38	Deletion	TTK

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

spindle organization
mitotic spindle organization
mitotic spindle assembly checkpoint
positive regulation of cell proliferation
positive regulation of pathway-restricted SMAD protein phosphorylation
peptidyl-tyrosine phosphorylation
chromosome separation

Function(s)

protein serine/threonine kinase activity
protein serine/threonine/tyrosine kinase activity
protein tyrosine kinase activity
protein binding
ATP binding