Hs02609769_cn

• Gene Symbol: DPYSL4
• Assay Reference Genome Location: Chr.10:132200471 on build GRCh38
• Cytoband: 10q26.3

Target Gene Details

• Entrez Gene ID: 10570
• Gene Name: dihydropyrimidinase like 4
• Gene Aliases: CRMP3, DRP-4, ULIP4
• Location: Chr.10:132184983-132205776 on Build GRCh38
• Assay Gene Location: Overlaps Exon 12 - Intron 12

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
DPYSL4	NM_006426.2			NP_006417.2
	XM_005252658.3			XP_005252715.1
	XM_011539125.2			XP_011537427.1
	XM_017015482.1			XP_016870971.1
	XM_017015483.1			XP_016870972.1
	AB006713.1			BAA21886.1
	BC136329.1
	BC136330.1
	Y10976.1			CAA71872.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1054569	Chr.10:132009350 - 132351508 on Build GRCh38	Gain	JAKMIP3 STK32C LRRC27 DPYSL4
esv3624956	Chr.10:131249138 - 132223150 on Build GRCh38	Gain	LINC01164 JAKMIP3 PPP2R2D STK32C BNIP3 TCERG1L DPYSL4
esv2761642	Chr.10:132048518 - 132365985 on Build GRCh38	Gain	JAKMIP3 STK32C LRRC27 DPYSL4
nsv1054934	Chr.10:130334322 - 133158679 on Build GRCh38	Gain	MIR378C TCERG1L-AS1 LINC01166 INPP5A JAKMIP3 C10orf91 PPP2R2D STK32C BNIP3 TCERG1L LINC01168 ADGRA1-AS1 LRRC27 LINC01164 CFAP46 PWWP2B ADGRA1 LOC107984282 LOC105378568 LINC01167 NKX6-2 DPYSL4
nsv951885	Chr.10:132093297 - 132212896 on Build GRCh38	Deletion	JAKMIP3 STK32C DPYSL4
nsv552504	Chr.10:132180474 - 132255847 on Build GRCh38	Loss	JAKMIP3 STK32C DPYSL4
nsv552502	Chr.10:132139965 - 132247418 on Build GRCh38	Loss	JAKMIP3 STK32C DPYSL4
nsv832030	Chr.10:132093129 - 132236507 on Build GRCh38	Loss	JAKMIP3 STK32C DPYSL4

More Information

Additional Information:

For this assay, SNP(s) [rs114312744] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

hydrolase

Gene Ontology Categories:

Process(es)

nervous system development
neuron death
neuron projection guidance

Function(s)

protein binding
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
filamin binding