Hs02610579_cn

• Gene Symbol: SKP1
• Assay Reference Genome Location: Chr.5:134158364 on build GRCh38
• Cytoband: 5q31.1

Target Gene Details

• Entrez Gene ID: 6500
• Gene Name: S-phase kinase-associated protein 1
• Gene Aliases: EMC19, OCP-II, OCP2, SKP1A, TCEB1L, p19A
• Location: Chr.5:134156391-134177033 on Build GRCh38
• Assay Gene Location: Within Exon 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SKP1	NM_006930.3	5	726	NP_008861.2
	NM_170679.2			NP_733779.1
	AK057110.1	2	1143
	BC009839.2			AAH09839.1
	BC020798.1			AAH20798.1
	BC025673.1	5	623	AAH25673.1
	BC065730.1			AAH65730.1
	BI552966.1
	BI670085.1
	U33760.1			AAC50241.1
	U37558.1			AAA79202.1
	Z47087.1			CAA87392.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv599732	Chr.5:134099223 - 134230401 on Build GRCh38	Loss	TCF7 PPP2CA MIR3661 SKP1

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

G2/M transition of mitotic cell cycle
protein polyubiquitination
stimulatory C-type lectin receptor signaling pathway
Wnt signaling pathway
protein ubiquitination
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
histone H2A monoubiquitination
NIK/NF-kappaB signaling
Fc-epsilon receptor signaling pathway
proteasome-mediated ubiquitin-dependent protein catabolic process
T cell receptor signaling pathway
stress-activated MAPK cascade
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition

Function(s)

ubiquitin-protein transferase activity
protein binding
beta-catenin binding
ubiquitin protein ligase activity
cullin family protein binding