Hs02641783_cn

• Gene Symbol: F11
• Assay Reference Genome Location: Chr.4:186288391 on build GRCh38
• Cytoband: 4q35.2

Target Gene Details

• Entrez Gene ID: 2160
• Gene Name: coagulation factor XI
• Gene Aliases: FXI
• Location: Chr.4:186265945-186290727 on Build GRCh38
• Assay Gene Location: Within Intron 14

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
F11	NM_000128.3			NP_000119.1
	XM_005262821.3			XP_005262878.1
	XM_005262822.3			XP_005262879.1
	XM_005262823.3			XP_005262880.1
	XM_006714137.2			XP_006714200.1
	AF045649.1			AAC24506.1
	AK313195.1
	BC119014.1
	BC122863.1
	M13142.1			AAA52487.1

Target Gene Details

• Entrez Gene ID: 285441
• Gene Name: F11 antisense RNA 1
• Gene Aliases: -
• Location: Chr.4:186286098-186501058 on Build GRCh38
• Assay Gene Location: Overlaps Intron 9 - Exon 9

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
F11-AS1	NR_033900.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1034638	Chr.4:186264231 - 186292323 on Build GRCh38	Loss	F11 F11-AS1
nsv1028146	Chr.4:185582745 - 186417181 on Build GRCh38	Gain	FAM149A TLR3 KLKB1 F11 F11-AS1 FLJ38576 CYP4V2 SORBS2
nsv461864	Chr.4:186085652 - 186335850 on Build GRCh38	Gain	FAM149A TLR3 KLKB1 F11 F11-AS1 FLJ38576 CYP4V2
nsv596401	Chr.4:186151229 - 186445495 on Build GRCh38	Loss	FAM149A KLKB1 F11 F11-AS1 FLJ38576 CYP4V2

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

serine protease

Gene Ontology Categories:

Process(es)

blood coagulation
blood coagulation, intrinsic pathway
plasminogen activation
positive regulation of fibrinolysis

Function(s)

serine-type endopeptidase activity
protein binding
heparin binding
serine-type aminopeptidase activity