Hs02666173_cn

• Gene Symbol: PTPRN
• Assay Reference Genome Location: Chr.2:219289595 on build GRCh38
• Cytoband: 2q35

Target Gene Details

• Entrez Gene ID: 5798
• Gene Name: protein tyrosine phosphatase, receptor type N
• Gene Aliases: IA-2, IA-2/PTP, IA2, ICA512, R-PTP-N
• Location: Chr.2:219289623-219309573 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 24

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PTPRN	NM_001199763.1			NP_001186692.1
	NM_001199764.1			NP_001186693.1
	NM_002846.3			NP_002837.1
	XM_011511566.1			XP_011509868.1
	XM_017004609.1			XP_016860098.1
	XM_017004610.1			XP_016860099.1
	XM_017004611.1			XP_016860100.1
	XM_017004612.1			XP_016860101.1
	AB209368.1			BAD92605.1
	AK054765.1
	AK122679.1
	BC007713.2			AAH07713.2
	BC070053.1			AAH70053.1
	L18983.1			AAA90974.1
	X62899.2			CAA44688.2

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv584501	Chr.2:219260522 - 219323181 on Build GRCh38	Loss	TUBA4B PTPRN MIR153-1 DNAJB2
nsv527936	Chr.2:219270486 - 219328674 on Build GRCh38	Loss	TUBA4B PTPRN MIR153-1 RESP18 DNAJB2
nsv834543	Chr.2:219226398 - 219416430 on Build GRCh38	Loss	TUBA4B ATG9A PTPRN GLB1L STK16 TUBA4A MIR153-1 RESP18 ANKZF1 DNPEP DNAJB2
nsv508885	Chr.2:219231225 - 219333602 on Build GRCh38	Insertion	TUBA4B PTPRN GLB1L STK16 TUBA4A MIR153-1 RESP18 ANKZF1 DNAJB2

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

protein phosphatase, protein modifying enzyme

Gene Ontology Categories:

Process(es)

response to reactive oxygen species
luteinization
cytokine-mediated signaling pathway
insulin secretion
response to insulin
insulin secretion involved in cellular response to glucose stimulus
response to estrogen
response to cAMP
dense core granule maturation

Function(s)

protein tyrosine phosphatase activity
protein binding
spectrin binding
GTPase binding