Hs02680911_cn

• Gene Symbol: MAN2B2
• Assay Reference Genome Location: Chr.4:6600678 on build GRCh38
• Cytoband: 4p16.1

Target Gene Details

• Entrez Gene ID: 23324
• Gene Name: mannosidase alpha class 2B member 2
• Gene Aliases: -
• Location: Chr.4:6575174-6622403 on Build GRCh38
• Assay Gene Location: Within Exon 10

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MAN2B2	NM_001292038.1	10	1345	NP_001278967.1
	NM_015274.2	10	1498	NP_056089.1
	AB023152.2	10	1457	BAA76779.2
	AK025803.1	2	126
	AK301473.1	10	1330
	AL832232.1	10	1468
	AL833071.2	10	1471	CAD89971.1
	BC033307.1	10	1467	AAH33307.1
	BC094773.1	10	1498	AAH94773.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv829849	Chr.4:6503821 - 6698228 on Build GRCh38	Loss	MAN2B2 PPP2R2C LOC339988 MRFAP1 LOC105374366 LOC93622 S100P
nsv949778	Chr.4:6560274 - 6626273 on Build GRCh38	Deletion	MAN2B2 PPP2R2C
nsv470006	Chr.4:6576760 - 6615221 on Build GRCh38	Loss	MAN2B2
nsv1007724	Chr.4:6586380 - 6611657 on Build GRCh38	Gain	MAN2B2

More Information

Additional Information:

For this assay, SNP(s) [rs73796294] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

mannose metabolic process
protein deglycosylation
oligosaccharide catabolic process

Function(s)

alpha-mannosidase activity
zinc ion binding
mannan endo-1,6-alpha-mannosidase activity
carbohydrate binding