Hs02688795_cn

• Gene Symbol: PRH1
• Assay Reference Genome Location: Chr.12:10997852 on build GRCh38
• Cytoband: 12p13.2

Target Gene Details

• Entrez Gene ID: 5554
• Gene Name: proline rich protein HaeIII subfamily 1
• Gene Aliases: Db-s, PA, PIF-S, PRH2, Pr1/Pr2
• Location: Chr.12:10880961-11171623 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PRH1	NM_001291314.1			NP_001278243.1
	NM_001291315.1			NP_001278244.1
	NR_133575.1
	AB593028.1
	AB593029.1
	BI772091.1
	BM476484.1
	BU543118.1

Target Gene Details

• Entrez Gene ID: 100533464
• Gene Name: PRH1-PRR4 readthrough
• Gene Aliases: PRH1
• Location: Chr.12:10845849-11171625 on Build GRCh38
• Assay Gene Location: Within Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PRH1-PRR4	NR_037918.2
	AB593030.1

Target Gene Details

• Entrez Gene ID: 259295
• Gene Name: taste 2 receptor member 20
• Gene Aliases: T2R20, T2R49, T2R56, TAS2R49
• Location: Chr.12:10995962-10997875 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TAS2R20	NM_176889.2			NP_795370.2
	BC100915.2			AAI00916.1
	BC100916.2			AAI00917.1
	BC100917.2			AAI00918.1
	BC100918.2			AAI00919.1
	BC113843.1			AAI13844.1
	BC114451.1			AAI14452.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv26197	Chr.12:10989558 - 11016859 on Build GRCh38	Gain	TAS2R20 PRH1 PRH1-PRR4 PRH1-TAS2R14
esv2664609	Chr.12:10995640 - 11052917 on Build GRCh38	Deletion	TAS2R20 PRH1 TAS2R19 PRH1-PRR4 PRH1-TAS2R14 TAS2R31
nsv1159978	Chr.12:10991920 - 11021118 on Build GRCh38	Duplication	TAS2R20 PRH1 PRH1-PRR4 PRH1-TAS2R14
esv3628556	Chr.12:10995613 - 11052888 on Build GRCh38	Loss	TAS2R20 PRH1 TAS2R19 PRH1-PRR4 PRH1-TAS2R14 TAS2R31
nsv832330	Chr.12:10925079 - 11054358 on Build GRCh38	Gain	TAS2R20 TAS2R14 PRH1 TAS2R50 TAS2R19 PRH2 PRH1-PRR4 PRH1-TAS2R14 TAS2R31
esv2759879	Chr.12:10817021 - 11561987 on Build GRCh38	Loss	TAS2R20 TAS2R10 TAS2R14 PRH1 PRB4 PRB1 TAS2R50 TAS2R19 PRH1-PRR4 TAS2R13 PRB2 PRB3 TAS2R43 TAS2R42 PRR4 PRH2 TAS2R30 PRH1-TAS2R14 LINC01252 TAS2R46 SMIM10L1 TAS2R31
esv8289	Chr.12:10991798 - 11069760 on Build GRCh38	Loss	TAS2R20 PRH1 TAS2R19 PRH1-PRR4 PRH1-TAS2R14 TAS2R46 TAS2R31
nsv1038277	Chr.12:10908379 - 11351157 on Build GRCh38	Loss	TAS2R20 TAS2R14 PRH1 PRB4 TAS2R50 TAS2R19 PRH1-PRR4 TAS2R13 PRB3 TAS2R43 TAS2R42 PRH2 TAS2R30 PRH1-TAS2R14 TAS2R46 SMIM10L1 TAS2R31
esv2745546	Chr.12:10980833 - 11078852 on Build GRCh38	Deletion	TAS2R20 PRH1 TAS2R50 TAS2R19 PRH1-PRR4 PRH1-TAS2R14 TAS2R46 TAS2R31
nsv428272	Chr.12:10917246 - 11561987 on Build GRCh38	Gain+Loss	TAS2R20 TAS2R14 PRH1 PRB4 PRB1 TAS2R50 TAS2R19 PRH1-PRR4 PRB2 PRB3 TAS2R43 TAS2R42 PRH2 TAS2R30 PRH1-TAS2R14 LINC01252 TAS2R46 SMIM10L1 TAS2R31

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

antimicrobial response protein, transmembrane signal receptor

Gene Ontology Categories:

Process(es)

detection of chemical stimulus involved in sensory perception of bitter taste
G-protein coupled receptor signaling pathway

Function(s)

protein binding
G-protein coupled receptor activity
bitter taste receptor activity