Hs02728765_cn

• Gene Symbol: NFS1
• Assay Reference Genome Location: Chr.20:35669713 on build GRCh38
• Cytoband: 20q11.22

Target Gene Details

• Entrez Gene ID: 9054
• Gene Name: NFS1 cysteine desulfurase
• Gene Aliases: HUSSY-08, IscS, NIFS
• Location: Chr.20:35668688-35699365 on Build GRCh38
• Assay Gene Location: Overlaps Intron 13 - Exon 14

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NFS1	NM_001198989.1			NP_001185918.1
	NM_021100.4			NP_066923.3
	NR_037570.2
	AF097025.2			AAD09187.2
	AJ010952.1			CAA09424.1
	AK001265.1
	AK001470.1
	AK056242.1
	AK091049.1
	AK223239.1			BAD96959.1
	AK297969.1
	AK301969.1
	AK302023.1
	AK312293.1
	BC065560.1			AAH65560.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv526188	Chr.20:35576541 - 36019079 on Build GRCh38	Gain	NFS1 SPAG4 CNBD2 SCAND1 RBM39 CPNE1 ROMO1 FER1L4 PHF20 RBM12

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

lyase, metabolite interconversion enzyme

Gene Ontology Categories:

Process(es)

sulfur amino acid metabolic process
protein complex assembly
Mo-molybdopterin cofactor biosynthetic process
iron incorporation into metallo-sulfur cluster
molybdopterin cofactor biosynthetic process
small molecule metabolic process
[2Fe-2S] cluster assembly

Function(s)

protein binding
pyridoxal phosphate binding
cysteine desulfurase activity
protein homodimerization activity
metal ion binding
iron-sulfur cluster binding