Hs02740534_cn

• Gene Symbol: GDF10
• Assay Reference Genome Location: Chr.10:47313232 on build GRCh38
• Cytoband: 10q11.22

Target Gene Details

• Entrez Gene ID: 2662
• Gene Name: growth differentiation factor 10
• Gene Aliases: BMP-3b, BMP3B
• Location: Chr.10:47300224-47313577 on Build GRCh38
• Assay Gene Location: Within Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GDF10	NM_004962.3	3	2305	NP_004953.1
	AA018253.1	1	342
	BC028237.1	3	1735	AAH28237.1
	D49492.1	3	2143	BAA08452.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv831861	Chr.10:47306097 - 47471541 on Build GRCh38	Loss	ZNF488 RBP3 GDF10 LOC105378292 ANXA8 LOC107001062 GDF2

More Information

Additional Information:

For this assay, SNP(s) [rs74910296] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

growth factor

Gene Ontology Categories:

Process(es)

skeletal system development
osteoblast differentiation
transforming growth factor beta receptor signaling pathway
positive regulation of pathway-restricted SMAD protein phosphorylation
BMP signaling pathway
regulation of apoptotic process
regulation of MAPK cascade
fat cell differentiation
negative regulation of osteoblast differentiation
cell development
SMAD protein signal transduction

Function(s)

cytokine activity
transforming growth factor beta receptor binding
growth factor activity