Hs02742038_cn

• Gene Symbol: NKX2-3
• Assay Reference Genome Location: Chr.10:99536349 on build GRCh38
• Cytoband: 10q24.2

Target Gene Details

• Entrez Gene ID: 159296
• Gene Name: NK2 homeobox 3
• Gene Aliases: CSX3, NK2.3, NKX2.3, NKX2C, NKX4-3
• Location: Chr.10:99532933-99536524 on Build GRCh38
• Assay Gene Location: Within Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NKX2-3	NM_145285.2	2	1922	NP_660328.2
	AK300856.1	2	1874
	BC025788.1	3	1805	AAH25788.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv831958	Chr.10:99451304 - 99651424 on Build GRCh38	Gain	SLC25A28 LINC01475 NKX2-3

More Information

Additional Information:

For this assay, SNP(s) [rs78952335] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

homeodomain transcription factor

Gene Ontology Categories:

Process(es)

leukocyte homeostasis
plasma cell differentiation
transcription, DNA-templated
triglyceride metabolic process
biological_process
gland morphogenesis
macrophage differentiation
regulation of cell proliferation
odontogenesis of dentin-containing tooth
CD4-positive, alpha-beta T cell differentiation
positive regulation of transcription from RNA polymerase II promoter
lymph node development
spleen development
Peyer's patch development
post-embryonic digestive tract morphogenesis
leukocyte migration

Function(s)

molecular_function
sequence-specific DNA binding