Hs02746716_cn

• Gene Symbol: CASP7
• Assay Reference Genome Location: Chr.10:113679196 on build GRCh38
• Cytoband: 10q25.3

Target Gene Details

• Entrez Gene ID: 840
• Gene Name: caspase 7
• Gene Aliases: CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3
• Location: Chr.10:113679162-113730909 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CASP7	NM_001267056.1			NP_001253985.1
	NM_001320911.1			NP_001307840.1
	NM_033340.3			NP_203126.1
	BX487250.1
	BX647973.1
	DC364916.1
	DC375817.1
	DC405356.1
	DC407017.1
	U37449.1			AAC50304.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3624603	Chr.10:113581857 - 113745416 on Build GRCh38	Gain	NRAP CASP7 HABP2
nsv1048819	Chr.10:113499347 - 113757619 on Build GRCh38	Gain	NRAP PLEKHS1 CASP7 HABP2
esv3577738	Chr.10:113598193 - 113692546 on Build GRCh38	Gain	NRAP CASP7
esv2741073	Chr.10:113678201 - 113679415 on Build GRCh38	Deletion	CASP7

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

protease

Gene Ontology Categories:

Process(es)

proteolysis
apoptotic process
cellular component disassembly involved in execution phase of apoptosis
activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c
execution phase of apoptosis

Function(s)

cysteine-type endopeptidase activity
protein binding
cysteine-type peptidase activity
cysteine-type endopeptidase activity involved in execution phase of apoptosis