Hs02752449_cn

• Gene Symbol: MTO1
• Assay Reference Genome Location: Chr.6:73497832 on build GRCh38
• Cytoband: 6q13

Target Gene Details

• Entrez Gene ID: 25821
• Gene Name: mitochondrial tRNA translation optimization 1
• Gene Aliases: CGI-02, COXPD10
• Location: Chr.6:73461727-73501456 on Build GRCh38
• Assay Gene Location: Within Exon 14

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MTO1	NM_001123226.1	12	2097	NP_001116698.1
	NM_012123.3	11	1977	NP_036255.2
	NM_133645.2	12	2052	NP_598400.1
	XM_006715444.2	11	1874	XP_006715507.1
	XM_006715445.2	11	1679	XP_006715508.1
	XM_006715446.3			XP_006715509.1
	XM_011535723.1	12	2066	XP_011534025.1
	XM_011535724.1	12	1934	XP_011534026.1
	XM_011535725.2	12	1802	XP_011534027.1
	XM_017010697.1			XP_016866186.1
	XM_017010698.1			XP_016866187.1
	XM_017010699.1	10	1399	XP_016866188.1
	XM_017010700.1	10	1671	XP_016866189.1
	AF132937.1	11	1899	AAD27712.1
	AF319422.2	11	1943	AAG42814.3
	AF469110.1	10	1652	AAL82394.1
	AF469111.1	10	2033	AAL82395.1
	AJ420530.1	10	1886
	AK026073.1	7	961
	AK074625.1	11	1956
	AK225828.1	12	2081
	AL833823.1	11	1821	CAD38685.1
	AY078985.1	12	2018	AAL85490.1
	AY078986.1	12	2018	AAL85491.1
	BC005808.2	12	1737	AAH05808.2
	BC011051.1	11	1918

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2763576	Chr.6:73487915 - 73567526 on Build GRCh38	Gain	EEF1A1 MTO1
nsv830693	Chr.6:73339619 - 73506357 on Build GRCh38	Loss	KHDC3L DDX43 MB21D1 DPPA5 MTO1 OOEP-AS1 OOEP

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

tRNA methylation
oxidation-reduction process
mitochondrial tRNA wobble uridine modification

Function(s)

oxidoreductase activity
poly(A) RNA binding
flavin adenine dinucleotide binding