Hs02790087_cn

• Gene Symbol: MTO1
• Assay Reference Genome Location: Chr.6:73466282 on build GRCh38
• Cytoband: 6q13

Target Gene Details

• Entrez Gene ID: 25821
• Gene Name: mitochondrial tRNA translation optimization 1
• Gene Aliases: CGI-02, COXPD10
• Location: Chr.6:73461727-73501456 on Build GRCh38
• Assay Gene Location: Within Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MTO1	NM_001123226.1	2	415	NP_001116698.1
	NM_012123.3	2	415	NP_036255.2
	NM_133645.2	2	415	NP_598400.1
	XM_006715444.2	2	312	XP_006715507.1
	XM_006715445.2	2	117	XP_006715508.1
	XM_006715446.3	2	415	XP_006715509.1
	XM_011535723.1	2	406	XP_011534025.1
	XM_011535724.1	2	274	XP_011534026.1
	XM_011535725.2	2	142	XP_011534027.1
	XM_017010697.1	2	312	XP_016866186.1
	XM_017010698.1	2	406	XP_016866187.1
	XM_017010699.1	2	127	XP_016866188.1
	XM_017010700.1	2	399	XP_016866189.1
	AF132937.1	2	337	AAD27712.1
	AF319422.2	2	381	AAG42814.3
	AF469110.1	2	381	AAL82394.1
	AF469111.1	2	381	AAL82395.1
	AJ420530.1	2	362
	AK074625.1	2	394
	AK225828.1	2	399
	AL833823.1	2	259	CAD38685.1
	AY078985.1	2	381	AAL85490.1
	AY078986.1	2	381	AAL85491.1
	BC005808.2	2	100	AAH05808.2
	BC011051.1	2	356
	DN993156.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3576177	Chr.6:73460675 - 73492915 on Build GRCh38	Gain	MTO1
nsv830693	Chr.6:73339619 - 73506357 on Build GRCh38	Loss	MB21D1 MTO1 OOEP DPPA5 KHDC3L DDX43 OOEP-AS1

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

tRNA methylation
oxidation-reduction process
mitochondrial tRNA wobble uridine modification

Function(s)

oxidoreductase activity
poly(A) RNA binding
flavin adenine dinucleotide binding