Hs02806917_cn

• Gene Symbol: RPA3
• Assay Reference Genome Location: Chr.7:7718586 on build GRCh38
• Cytoband: 7p21.3

Target Gene Details

• Entrez Gene ID: 6119
• Gene Name: replication protein A3
• Gene Aliases: REPA3, RP-A p14
• Location: Chr.7:7636563-7718607 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
RPA3	NM_002947.4			NP_002938.1
	BC009868.2			AAH09868.1

Target Gene Details

• Entrez Gene ID: 729852
• Gene Name: UBAP1-MVB12-associated (UMA) domain containing 1
• Gene Aliases: RPA3-AS1, RPA3OS
• Location: Chr.7:7640636-7879223 on Build GRCh38
• Assay Gene Location: Within Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
UMAD1	NM_001302348.1			NP_001289277.1
	NM_001302349.1			NP_001289278.1
	NM_001302350.1			NP_001289279.1
	AK295253.1
	DA576342.1
	DA678734.1
	DC313244.1
	DC340488.1
	DC354992.1
	DC368552.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv6249n100	Chr.7:6962401 - 8039172 on Build GRCh38	Gain	GLCCI1 MIOS LOC101927354 LOC100505921 COL28A1 C1GALT1 LOC101927391 LOC100131257 UMAD1 MIR3683 RPA3
esv2752174	Chr.7:6648102 - 7734210 on Build GRCh38	Gain	RSPH10B2 LOC101927354 ZNF12 UMAD1 MIR3683 ZNF316 RPA3 PMS2CL LOC100419773 MIOS COL28A1 C1GALT1 LOC101927391 LOC100131257 CCZ1B
esv2752177	Chr.7:7689616 - 8138059 on Build GRCh38	Gain	GLCCI1 LOC100505921 ICA1 UMAD1 RPA3
nsv8043	Chr.7:7549564 - 7823171 on Build GRCh38	Gain	MIOS LOC101927391 UMAD1 RPA3
esv3891036	Chr.7:7491637 - 7877729 on Build GRCh38	Gain	MIOS COL28A1 LOC101927391 UMAD1 RPA3
nsv606042	Chr.7:7387904 - 7836835 on Build GRCh38	Gain	MIOS COL28A1 LOC101927391 UMAD1 RPA3
esv2761144	Chr.7:7457249 - 8757480 on Build GRCh38	Gain+Loss	GLCCI1 MIOS LOC100505921 NXPH1 COL28A1 LOC101927391 LOC100505938 ICA1 UMAD1 RPA3

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

G1/S transition of mitotic cell cycle
telomere maintenance via recombination
double-strand break repair via homologous recombination
DNA replication
transcription-coupled nucleotide-excision repair
base-excision repair
nucleotide-excision repair
nucleotide-excision repair, preincision complex stabilization
nucleotide-excision repair, preincision complex assembly
nucleotide-excision repair, DNA incision, 3'-to lesion
nucleotide-excision repair, DNA incision, 5'-to lesion
nucleotide-excision repair, DNA gap filling
mismatch repair
regulation of mitotic cell cycle
translesion synthesis
nucleotide-excision repair, DNA incision
interstrand cross-link repair
regulation of cell proliferation
error-prone translesion synthesis
DNA damage response, detection of DNA damage
error-free translesion synthesis
regulation of cellular response to heat
regulation of signal transduction by p53 class mediator

Function(s)

damaged DNA binding
single-stranded DNA binding
protein binding