Hs02808127_cn

• Gene Symbol: FOXA1
• Assay Reference Genome Location: Chr.14:37590941 on build GRCh38
• Cytoband: 14q21.1

Target Gene Details

• Entrez Gene ID: 3169
• Gene Name: forkhead box A1
• Gene Aliases: HNF3A, TCF3A
• Location: Chr.14:37589552-37595120 on Build GRCh38
• Assay Gene Location: Within Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
FOXA1	NM_004496.3	2	1991	NP_004487.2
	XM_017021246.1	2	2553	XP_016876735.1
	BC033890.1	2	1905	AAH33890.1
	U39840.1	2	1930	AAB06493.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv832772	Chr.14:37561095 - 37756716 on Build GRCh38	Loss	MIPOL1 TTC6 FOXA1
nsv826923	Chr.14:37548414 - 37639440 on Build GRCh38	Gain	MIPOL1 TTC6 FOXA1

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

winged helix/forkhead transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
chromatin remodeling
transcription from RNA polymerase II promoter
Notch signaling pathway
negative regulation of epithelial to mesenchymal transition
covalent chromatin modification
dorsal/ventral neural tube patterning
response to estradiol
positive regulation of intracellular estrogen receptor signaling pathway
hormone metabolic process
glucose homeostasis
positive regulation of neuron differentiation
positive regulation of smoothened signaling pathway
positive regulation of mitotic cell cycle
positive regulation of transcription from RNA polymerase II promoter
anatomical structure formation involved in morphogenesis
neuron fate specification
positive regulation of sequence-specific DNA binding transcription factor activity
epithelial tube branching involved in lung morphogenesis
lung epithelial cell differentiation
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development
epithelial-mesenchymal signaling involved in prostate gland development
prostate gland epithelium morphogenesis
prostate gland stromal morphogenesis
epithelial cell maturation involved in prostate gland development
alveolar secondary septum development
dopaminergic neuron differentiation
respiratory basal cell differentiation
positive regulation of cell-cell adhesion mediated by cadherin

Function(s)

RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription factor binding
protein domain specific binding
sequence-specific DNA binding
transcription regulatory region DNA binding