Hs02818015_cn

• Gene Symbol: WARS
• Assay Reference Genome Location: Chr.14:100337239 on build GRCh38
• Cytoband: 14q32.2

Target Gene Details

• Entrez Gene ID: 7453
• Gene Name: tryptophanyl-tRNA synthetase
• Gene Aliases: GAMMA-2, IFI53, IFP53
• Location: Chr.14:100333788-100376343 on Build GRCh38
• Assay Gene Location: Within Intron 12

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
WARS	NM_004184.3			NP_004175.2
	NM_173701.1			NP_776049.1
	NM_213645.1			NP_998810.1
	NM_213646.1			NP_998811.1
	XM_005268044.3			XP_005268101.1
	XM_006720249.3			XP_006720312.1
	XM_011537133.2			XP_011535435.1
	XM_011537135.2			XP_011535437.1
	XM_011537136.2			XP_011535438.1
	XM_017021627.1			XP_016877116.1
	XM_017021628.1			XP_016877117.1
	XM_017021629.1			XP_016877118.1
	AK025487.1
	AK056100.1
	AK130698.1
	AK291141.1
	BC017489.1			AAH17489.1
	BC095453.1			AAH95453.1
	BX248006.1			CAD62335.1
	M61715.1			AAA61298.1
	M77804.1			AAA67324.1
	X59892.1			CAA42545.1
	X62570.1			CAA44450.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv832875	Chr.14:100192592 - 100368905 on Build GRCh38	Loss	MIR6764 WARS MIR345 SLC25A29 YY1 SLC25A47

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

aminoacyl-tRNA synthetase

Gene Ontology Categories:

Process(es)

angiogenesis
translation
tRNA aminoacylation for protein translation
tryptophanyl-tRNA aminoacylation
negative regulation of cell proliferation
regulation of angiogenesis

Function(s)

tryptophan-tRNA ligase activity
protein binding
ATP binding