Hs02832218_cn

• Gene Symbol: DENND5B
• Assay Reference Genome Location: Chr.12:31385237 on build GRCh38
• Cytoband: 12p11.21

Target Gene Details

• Entrez Gene ID: 160518
• Gene Name: DENN domain containing 5B
• Gene Aliases: -
• Location: Chr.12:31382223-31591018 on Build GRCh38
• Assay Gene Location: Within Exon 26

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
DENND5B	NM_001308339.1	23	6447	NP_001295268.1
	NM_144973.3	21	6377	NP_659410.3
	XM_005253326.2	23	6490	XP_005253383.1
	XM_005253327.3	22	6483	XP_005253384.1
	XM_005253330.3	23	5959	XP_005253387.1
	XM_006719040.3	22	6379	XP_006719103.1
	XM_011520590.2	20	5726	XP_011518892.1
	XM_017018896.1	21	6280	XP_016874385.1
	XM_017018897.1	23	6853	XP_016874386.1
	XM_017018898.1	22	5953	XP_016874387.1
	XM_017018899.1	22	5738	XP_016874388.1
	AB209341.1	17	5007	BAD92578.1
	AK021465.1	1	1090
	AK123642.1	4	2005
	BX537924.1	14	4150	CAD97905.1
	CR749639.1	9	3619	CAH18433.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2751046	Chr.12:31021299 - 31531799 on Build GRCh38	Gain	DDX11 LOC101929027 DDX11-AS1 OVOS2 DENND5B FLJ13224 FAM60A
nsv832364	Chr.12:31315056 - 31495210 on Build GRCh38	Loss	LOC101929027 DENND5B FLJ13224 FAM60A

More Information

Additional Information:

For this assay, SNP(s) [rs73288135] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

positive regulation of GTPase activity
detection of mechanical stimulus
calcium ion transmembrane transport

Function(s)

calcium channel activity
Rab guanyl-nucleotide exchange factor activity