Hs02868296_cn

• Gene Symbol: TLR8
• Assay Reference Genome Location: Chr.X:12922677 on build GRCh38
• Cytoband: Xp22.2

Target Gene Details

• Entrez Gene ID: 51311
• Gene Name: toll like receptor 8
• Gene Aliases: CD288
• Location: Chr.X:12906620-12923169 on Build GRCh38
• Assay Gene Location: Within Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TLR8	NM_016610.3	3	3861	NP_057694.2
	NM_138636.5	2	3724	NP_619542.1
	XM_011545529.1	3	4012	XP_011543831.1
	XM_011545530.2	3	3840	XP_011543832.1
	AK075117.1	1	1202	BAC11412.1
	AY358296.1	2	3693	AAQ88663.1

Target Gene Details

• Entrez Gene ID: 349408
• Gene Name: TLR8 antisense RNA 1
• Gene Aliases: GS1-324M7.6
• Location: Chr.X:12902817-12943300 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TLR8-AS1	NR_030727.1
	BI907428.1

More Information

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, non-DGV Variation

Gene Ontology Categories:

Process(es)

microglial cell activation
regulation of protein phosphorylation
toll-like receptor signaling pathway
MyD88-dependent toll-like receptor signaling pathway
inflammatory response
I-kappaB kinase/NF-kappaB signaling
response to virus
immunoglobulin mediated immune response
toll-like receptor 8 signaling pathway
toll-like receptor 9 signaling pathway
positive regulation of interferon-gamma biosynthetic process
innate immune response
positive regulation of innate immune response
positive regulation of interferon-alpha biosynthetic process
positive regulation of interferon-beta biosynthetic process
positive regulation of interleukin-8 biosynthetic process
regulation of cytokine secretion
defense response to virus
cellular response to mechanical stimulus

Function(s)

DNA binding
RNA binding
double-stranded RNA binding
single-stranded RNA binding
receptor activity
drug binding