Hs02975107_cn

• Gene Symbol: E2F4
• Assay Reference Genome Location: Chr.16:67198941 on build GRCh38
• Cytoband: 16q22.1

Target Gene Details

• Entrez Gene ID: 1874
• Gene Name: E2F transcription factor 4
• Gene Aliases: E2F-4
• Location: Chr.16:67192165-67198918 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 10

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
E2F4	NM_001950.3			NP_001941.2
	BC033180.1			AAH33180.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv522852	Chr.16:67153308 - 68071571 on Build GRCh38	Gain	NOL3 EXOC3L1 LOC100131303 GFOD2 LRRC36 ZDHHC1 SLC12A4 PSMB10 NRN1L DPEP3 E2F4 SLC9A5 ACD FBXL8 PSKH1 AGRP TPPP3 CARMIL2 DUS2 LRRC29 LOC100505942 THAP11 HSD11B2 LOC105369155 CENPT C16orf86 FAM65A PLEKHG4 ENKD1 KCTD19 CTCF ATP6V0D1 CTRL ELMO3 KIAA0895L TRADD DPEP2 FHOD1 DDX28 NUTF2 TSNAXIP1 HSF4 LOC107984813 PARD6A EDC4 MIR328 RANBP10 LCAT TMEM208
nsv827707	Chr.16:67148355 - 67289296 on Build GRCh38	Loss	NOL3 EXOC3L1 C16orf70 FBXL8 PLEKHG4 HSF4 LRRC29 ELMO3 KIAA0895L LOC105369155 MIR328 B3GNT9 TRADD FHOD1 E2F4 SLC9A5 TMEM208
nsv952044	Chr.16:67141198 - 67244397 on Build GRCh38	Deletion	NOL3 EXOC3L1 C16orf70 FBXL8 HSF4 LRRC29 ELMO3 KIAA0895L LOC105369155 MIR328 B3GNT9 TRADD FHOD1 E2F4 TMEM208
nsv1160429	Chr.16:67161549 - 67220197 on Build GRCh38	Deletion	NOL3 EXOC3L1 ELMO3 FBXL8 KIAA0895L LOC105369155 MIR328 HSF4 E2F4 LRRC29
nsv457513	Chr.16:67181417 - 67282697 on Build GRCh38	Loss	EXOC3L1 ELMO3 KIAA0895L PLEKHG4 LOC105369155 MIR328 FHOD1 E2F4 LRRC29 SLC9A5 TMEM208
nsv524492	Chr.16:67174030 - 67294550 on Build GRCh38	Loss	NOL3 EXOC3L1 PLEKHG4 KCTD19 LRRC29 ELMO3 KIAA0895L LOC105369155 MIR328 FHOD1 E2F4 SLC9A5 TMEM208
nsv524363	Chr.16:67136529 - 68071571 on Build GRCh38	Loss	NOL3 EXOC3L1 C16orf70 LOC100131303 GFOD2 LRRC36 ZDHHC1 SLC12A4 PSMB10 NRN1L B3GNT9 DPEP3 E2F4 SLC9A5 ACD FBXL8 PSKH1 AGRP TPPP3 CARMIL2 DUS2 LRRC29 LOC100505942 THAP11 HSD11B2 LOC105369155 CENPT C16orf86 FAM65A PLEKHG4 ENKD1 KCTD19 CTCF ATP6V0D1 CTRL ELMO3 KIAA0895L TRADD DPEP2 FHOD1 DDX28 NUTF2 TSNAXIP1 HSF4 LOC107984813 PARD6A EDC4 MIR328 RANBP10 LCAT TMEM208

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

RNA metabolism protein, nucleic acid metabolism protein, general transcription factor

Gene Ontology Categories:

Process(es)

regulation of transcription involved in G1/S transition of mitotic cell cycle
epithelial cell development
transcription from RNA polymerase II promoter
cell volume homeostasis
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
blood circulation
organ morphogenesis
regulation of cell proliferation
motile cilium assembly
positive regulation of transcription from RNA polymerase II promoter
centriole assembly
multi-ciliated epithelial cell differentiation

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
transcription factor binding
protein domain specific binding
promoter-specific chromatin binding