Hs03006962_cn

• Gene Symbol: MEIS3
• Assay Reference Genome Location: Chr.19:47419567 on build GRCh38
• Cytoband: 19q13.32

Target Gene Details

• Entrez Gene ID: 56917
• Gene Name: Meis homeobox 3
• Gene Aliases: MRG2
• Location: Chr.19:47403118-47422315 on Build GRCh38
• Assay Gene Location: Overlaps Intron 1 - Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MEIS3	NM_001009813.2			NP_001009813.1
	NM_001301059.1			NP_001287988.1
	NM_020160.2			NP_064545.1
	XM_011527139.2			XP_011525441.1
	CF993984.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3371880	Chr.19:47419534 - 47419576 on Build GRCh38	Insertion	MEIS3
nsv1057003	Chr.19:47416492 - 47471403 on Build GRCh38	Loss	MEIS3 SLC8A2
esv2758765	Chr.19:47354499 - 47522248 on Build GRCh38	Loss	NAPA MEIS3 DHX34 SLC8A2 NAPA-AS1 ZNF541 KPTN
nsv517901	Chr.19:47373953 - 47444971 on Build GRCh38	Loss	MEIS3 DHX34 SLC8A2
nsv9738	Chr.19:47356269 - 47427931 on Build GRCh38	Gain	MEIS3 DHX34
esv2479786	Chr.19:47418740 - 47420765 on Build GRCh38	Loss	MEIS3

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

homeodomain transcription factor

Gene Ontology Categories:

Process(es)

transcription from RNA polymerase II promoter
positive regulation of transcription from RNA polymerase II promoter
positive regulation of protein kinase B signaling
negative regulation of apoptotic signaling pathway

Function(s)

transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
chromatin binding
sequence-specific DNA binding