Hs03017651_cn

• Gene Symbol: RRM2
• Assay Reference Genome Location: Chr.2:10123577 on build GRCh38
• Cytoband: 2p25.1

Target Gene Details

• Entrez Gene ID: 6241
• Gene Name: ribonucleotide reductase regulatory subunit M2
• Gene Aliases: R2, RR2, RR2M
• Location: Chr.2:10122568-10131419 on Build GRCh38
• Assay Gene Location: Within Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
RRM2	NM_001034.3			NP_001025.1
	NM_001165931.1			NP_001159403.1
	AK092671.1
	AK123010.1
	AK313719.1
	BC001886.1			AAH01886.1
	BC030154.1			AAH30154.1
	S40301.1			AAA09577.1
	X59618.1			CAA42181.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv3715n100	Chr.2:10014833 - 10135998 on Build GRCh38	Gain	CYS1 LOC101929882 RRM2 KLF11

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

reductase

Gene Ontology Categories:

Process(es)

G1/S transition of mitotic cell cycle
regulation of transcription involved in G1/S transition of mitotic cell cycle
DNA replication
deoxyribonucleoside diphosphate metabolic process
deoxyribonucleotide biosynthetic process
nucleobase-containing small molecule interconversion
protein heterotetramerization
oxidation-reduction process

Function(s)

ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
protein binding
metal ion binding