Hs03040554_cn

• Gene Symbol: SIX4
• Assay Reference Genome Location: Chr.14:60712377 on build GRCh38
• Cytoband: 14q23.1

Target Gene Details

• Entrez Gene ID: 51804
• Gene Name: SIX homeobox 4
• Gene Aliases: AREC3
• Location: Chr.14:60709538-60724321 on Build GRCh38
• Assay Gene Location: Within Exon 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SIX4	NM_017420.4	3	3436	NP_059116.3
	XM_005267759.2	4	3415	XP_005267816.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv564880	Chr.14:60397865 - 60916029 on Build GRCh38	Gain	MNAT1 LOC105378189 C14orf39 SIX1 SIX6 SIX4 SALRNA1
nsv564881	Chr.14:60457291 - 61377535 on Build GRCh38	Gain	MNAT1 LOC105378189 C14orf39 TMEM30B SIX1 PRKCH TRMT5 SIX6 SLC38A6 SIX4 SALRNA1

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

homeodomain transcription factor

Gene Ontology Categories:

Process(es)

transcription from RNA polymerase II promoter
skeletal muscle tissue development
regulation of synaptic growth at neuromuscular junction
male gonad development
anatomical structure morphogenesis
male sex determination
olfactory placode formation
regulation of protein localization
protein localization to nucleus
inner ear morphogenesis
negative regulation of apoptotic process
negative regulation of neuron apoptotic process
tongue development
sarcomere organization
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
male sex differentiation
thymus development
generation of neurons
embryonic cranial skeleton morphogenesis
regulation of epithelial cell proliferation
myoblast migration
pharyngeal system development
myotome development
fungiform papilla morphogenesis
trigeminal ganglion development
metanephric mesenchyme development
regulation of branch elongation involved in ureteric bud branching
positive regulation of ureteric bud formation
positive regulation of branching involved in ureteric bud morphogenesis
skeletal muscle fiber differentiation
negative regulation of satellite cell differentiation

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding