Hs03050784_cn

• Gene Symbol: TRADD
• Assay Reference Genome Location: Chr.16:67155106 on build GRCh38
• Cytoband: 16q22.1

Target Gene Details

• Entrez Gene ID: 8717
• Gene Name: TNFRSF1A associated via death domain
• Gene Aliases: Hs.89862
• Location: Chr.16:67154185-67159909 on Build GRCh38
• Assay Gene Location: Overlaps Intron 5 - Exon 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TRADD	NM_001323552.1			NP_001310481.1
	NM_003789.3			NP_003780.1
	XM_005256213.3			XP_005256270.1
	XM_017023815.1			XP_016879304.1
	AK090673.1
	AK315654.1
	BC004491.2			AAH04491.1
	BT006934.1			AAP35580.1
	L41690.1			AAA98482.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv522852	Chr.16:67153308 - 68071571 on Build GRCh38	Gain	E2F4 TSNAXIP1 DPEP3 FAM65A RANBP10 GFOD2 HSF4 KCTD19 PLEKHG4 C16orf86 THAP11 CARMIL2 TPPP3 SLC12A4 EXOC3L1 ENKD1 LRRC29 FHOD1 NOL3 CTCF CENPT ZDHHC1 AGRP EDC4 ACD NRN1L SLC9A5 DUS2 TMEM208 LOC105369155 MIR328 LCAT LOC100505942 ELMO3 PSKH1 LRRC36 LOC107984813 LOC100131303 KIAA0895L FBXL8 CTRL PSMB10 ATP6V0D1 PARD6A NUTF2 DPEP2 TRADD HSD11B2 DDX28
nsv827707	Chr.16:67148355 - 67289296 on Build GRCh38	Loss	C16orf70 E2F4 KIAA0895L EXOC3L1 MIR328 FBXL8 LRRC29 FHOD1 NOL3 B3GNT9 ELMO3 SLC9A5 HSF4 PLEKHG4 TRADD TMEM208 LOC105369155
nsv952044	Chr.16:67141198 - 67244397 on Build GRCh38	Deletion	C16orf70 E2F4 KIAA0895L EXOC3L1 MIR328 FBXL8 LRRC29 FHOD1 NOL3 B3GNT9 ELMO3 HSF4 TRADD TMEM208 LOC105369155
nsv524363	Chr.16:67136529 - 68071571 on Build GRCh38	Loss	C16orf70 E2F4 TSNAXIP1 DPEP3 B3GNT9 FAM65A RANBP10 GFOD2 HSF4 KCTD19 PLEKHG4 C16orf86 THAP11 CARMIL2 TPPP3 SLC12A4 EXOC3L1 ENKD1 LRRC29 FHOD1 NOL3 CTCF CENPT ZDHHC1 AGRP EDC4 ACD NRN1L SLC9A5 DUS2 TMEM208 LOC105369155 MIR328 LCAT LOC100505942 ELMO3 PSKH1 LRRC36 LOC107984813 LOC100131303 KIAA0895L FBXL8 CTRL PSMB10 ATP6V0D1 PARD6A NUTF2 DPEP2 TRADD HSD11B2 DDX28

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
signal transduction
I-kappaB kinase/NF-kappaB signaling
extrinsic apoptotic signaling pathway via death domain receptors
regulation of tumor necrosis factor-mediated signaling pathway
regulation of necrotic cell death
tumor necrosis factor-mediated signaling pathway
positive regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of NF-kappaB transcription factor activity
protein heterooligomerization
positive regulation of hair follicle development
death-inducing signaling complex assembly
extrinsic apoptotic signaling pathway
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

Function(s)

signal transducer activity
tumor necrosis factor receptor binding
protein binding
kinase binding
protein complex binding
identical protein binding
binding, bridging
death domain binding