Hs03056799_cn

• Gene Symbol: CTSS
• Assay Reference Genome Location: Chr.1:150732301 on build GRCh38
• Cytoband: 1q21.3

Target Gene Details

• Entrez Gene ID: 1520
• Gene Name: cathepsin S
• Gene Aliases: -
• Location: Chr.1:150730196-150765957 on Build GRCh38
• Assay Gene Location: Within Exon 8

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CTSS	NM_001199739.1	7	1852	NP_001186668.1
	NM_004079.4	8	2002	NP_004070.3
	AK024855.1	1	191
	AK226095.1	8	1864

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1006838	Chr.1:150453465 - 150750307 on Build GRCh38	Gain	HORMAD1 TARS2 CTSS FALEC MIR4257 ENSA GOLPH3L LOC100289061 MIR6878 MCL1 LOC107983947 ADAMTSL4-AS1 RPRD2 ECM1 ADAMTSL4

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

cysteine protease

Gene Ontology Categories:

Process(es)

toll-like receptor signaling pathway
adaptive immune response
proteolysis
immune response
response to acidic pH
protein processing
antigen processing and presentation
antigen processing and presentation of exogenous peptide antigen via MHC class II
extracellular matrix disassembly
collagen catabolic process
basement membrane disassembly
antigen processing and presentation of peptide antigen
proteolysis involved in cellular protein catabolic process
cellular response to thyroid hormone stimulus
positive regulation of cation channel activity

Function(s)

fibronectin binding
cysteine-type endopeptidase activity
serine-type endopeptidase activity
collagen binding
laminin binding
proteoglycan binding