Hs03182512_cn

• Gene Symbol: CNTF
• Assay Reference Genome Location: Chr.11:58625676 on build GRCh38
• Cytoband: 11q12.1

Target Gene Details

• Entrez Gene ID: 1270
• Gene Name: ciliary neurotrophic factor
• Gene Aliases: HCNTF
• Location: Chr.11:58622673-58625733 on Build GRCh38
• Assay Gene Location: Within Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CNTF	NM_000614.3	2	1837	NP_000605.1
	BC068030.1	2	1832	AAH68030.1
	BC069167.1	2	1837	AAH69167.1
	DB341875.1	1	55

Target Gene Details

• Entrez Gene ID: 386607
• Gene Name: ZFP91-CNTF readthrough (NMD candidate)
• Gene Aliases: -
• Location: Chr.11:58579114-58625733 on Build GRCh38
• Assay Gene Location: Within Exon 13

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ZFP91-CNTF	NR_024091.1	13	3487

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1159883	Chr.11:58621846 - 58666718 on Build GRCh38	Duplication	CNTF ZFP91-CNTF

More Information

Additional Information:

• Set Membership: Intragenic, Exonic, DGV Variation, Validated

Gene Ontology Categories:

Process(es)

signal transduction
positive regulation of cell proliferation
positive regulation of gene expression
growth
positive regulation of tyrosine phosphorylation of Stat3 protein
negative regulation of neuron apoptotic process
negative regulation of photoreceptor cell differentiation
regulation of retinal cell programmed cell death
astrocyte activation
muscle organ morphogenesis
neuron development
positive regulation of axon regeneration
ciliary neurotrophic factor-mediated signaling pathway

Function(s)

cytokine activity
ciliary neurotrophic factor receptor binding
interleukin-6 receptor binding
protein binding
growth factor activity