Hs03383604_cn

• Gene Symbol: LOC149373
• Assay Reference Genome Location: Chr.1:231184641 on build GRCh38
• Cytoband: 1q42.2

Target Gene Details

• Entrez Gene ID: 149373
• Gene Name: uncharacterized LOC149373
• Gene Aliases: -
• Location: Chr.1:231184099-231187627 on Build GRCh38
• Assay Gene Location: Within Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LOC149373	NM_001256615.1	3	805	NP_001243544.1
	AK054992.1	1	1757	BAB70837.1

Target Gene Details

• Entrez Gene ID: 440730
• Gene Name: tripartite motif containing 67
• Gene Aliases: TNL
• Location: Chr.1:231162928-231221568 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TRIM67	NM_001004342.3			NP_001004342.3
	NM_001300889.1			NP_001287818.1
	XM_011544192.2			XP_011542494.1
	XM_017001323.1			XP_016856812.1
	AK126782.1			BAC86689.1
	AY253917.1			AAP69949.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3589106	Chr.1:231110289 - 231278336 on Build GRCh38	Gain	C1orf131 TRIM67 LOC149373 GNPAT
esv3589093	Chr.1:230482037 - 231277190 on Build GRCh38	Gain	TTC13 C1orf131 CAPN9 C1orf198 COG2 TRIM67 LOC149373 LOC101927604 ARV1 LOC101927553 GNPAT FAM89A MIR1182 AGT
esv3589108	Chr.1:231184125 - 231186232 on Build GRCh38	Loss	TRIM67 LOC149373
esv27426	Chr.1:231184167 - 231186292 on Build GRCh38	Loss	TRIM67 LOC149373
esv2669296	Chr.1:231184145 - 231186249 on Build GRCh38	Deletion	TRIM67 LOC149373
nsv1011066	Chr.1:230940432 - 231242850 on Build GRCh38	Gain	TTC13 C1orf131 TRIM67 FAM89A MIR1182 LOC149373 ARV1 GNPAT
nsv1000488	Chr.1:230799658 - 231269735 on Build GRCh38	Gain	TTC13 C1orf131 CAPN9 C1orf198 TRIM67 FAM89A MIR1182 LOC149373 LOC101927604 ARV1 GNPAT
nsv517116	Chr.1:231182932 - 231187593 on Build GRCh38	Loss	TRIM67 LOC149373
esv2764227	Chr.1:231176121 - 231188285 on Build GRCh38	Loss	TRIM67 LOC149373

More Information

Additional Information:

For this assay, SNP(s) [rs76044472] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

positive regulation of neuron projection development
negative regulation of Ras protein signal transduction
positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Function(s)

zinc ion binding