Hs03384451_cn

• Gene Symbol: ATF3
• Assay Reference Genome Location: Chr.1:212586643 on build GRCh38
• Cytoband: 1q32.3

Target Gene Details

• Entrez Gene ID: 467
• Gene Name: activating transcription factor 3
• Gene Aliases: -
• Location: Chr.1:212565334-212620777 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ATF3	NM_001030287.3			NP_001025458.1
	AU135799.1
	CD638624.1
	CD641946.1
	DA691940.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv549139	Chr.1:212158952 - 212703560 on Build GRCh38	Gain	NENF PPP2R5A SNORA16B BATF3 LOC101929565 TMEM206 FAM71A LOC101929541 ATF3
esv2758996	Chr.1:212474801 - 212669761 on Build GRCh38	Loss	LOC101929565 FAM71A ATF3

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

basic leucine zipper transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
gluconeogenesis
transcription from RNA polymerase II promoter
positive regulation of cell proliferation
cellular response to amino acid starvation
skeletal muscle cell differentiation
PERK-mediated unfolded protein response
positive regulation of transcription from RNA polymerase II promoter
regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance
negative regulation of ERK1 and ERK2 cascade
positive regulation of TRAIL-activated apoptotic signaling pathway
positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress

Function(s)

transcription regulatory region sequence-specific DNA binding
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
transcription corepressor activity
protein binding
identical protein binding
protein homodimerization activity
transcription regulatory region DNA binding
protein heterodimerization activity