Hs03513460_cn

• Gene Symbol: SPCS3
• Assay Reference Genome Location: Chr.4:176325006 on build GRCh38
• Cytoband: 4q34.2

Target Gene Details

• Entrez Gene ID: 60559
• Gene Name: signal peptidase complex subunit 3
• Gene Aliases: PRO3567, SPC22/23, SPC3, YLR066W
• Location: Chr.4:176319939-176332245 on Build GRCh38
• Assay Gene Location: Within Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SPCS3	NM_021928.3			NP_068747.1
	AK026302.1			BAB15437.1
	AK092634.1
	AL136660.1			CAB66595.1
	AY359044.1			AAQ89403.1
	BC047290.1			AAH47290.1
	DB285025.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3894072	Chr.4:176311557 - 176329340 on Build GRCh38	Loss	SPCS3
esv34137	Chr.4:175851071 - 176341258 on Build GRCh38	Loss	WDR17 ASB5 SPATA4 SPCS3 GPM6A
esv2728772	Chr.4:175817087 - 177875422 on Build GRCh38	Deletion	WDR17 LOC285500 VEGFC ASB5 LINC01098 SPATA4 AGA NEIL3 SPCS3 LINC01099 GPM6A
esv3603274	Chr.4:176144758 - 176386481 on Build GRCh38	Gain	WDR17 ASB5 SPATA4 SPCS3

More Information

Additional Information:

For this assay, SNP(s) [rs78453928] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

protease

Gene Ontology Categories:

Process(es)

signal peptide processing

Function(s)

peptidase activity