Hs03535335_cn

• Gene Symbol: NKX1-1
• Assay Reference Genome Location: Chr.4:1405686 on build GRCh38
• Cytoband: 4p16.3

Target Gene Details

• Entrez Gene ID: 54729
• Gene Name: NK1 homeobox 1
• Gene Aliases: HSPX153, NKX-1.1, SAX2
• Location: Chr.4:1402932-1406442 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NKX1-1	NM_001290079.1			NP_001277008.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1073288	Chr.4:1405211 - 1406812 on Build GRCh38	Deletion	NKX1-1
nsv822425	Chr.4:546316 - 1420011 on Build GRCh38	Loss	MFSD7 CPLX1 LOC107986211 CTBP1 FGFRL1 SLC26A1 PDE6B GAK IDUA MAEA UVSSA MYL5 LOC100130872 SPON2 CTBP1-AS2 DGKQ ATP5I TMED11P TMEM175 LOC105374344 LOC101928548 CTBP1-AS NKX1-1 LOC100129917 RNF212 PCGF3 CRIPAK LOC101928521
dgv853n67	Chr.4:1402664 - 1408969 on Build GRCh38	Gain	NKX1-1
nsv4197	Chr.4:1387665 - 1421471 on Build GRCh38	Insertion	UVSSA NKX1-1 CRIPAK
nsv593278	Chr.4:1165892 - 1421910 on Build GRCh38	Loss	MAEA UVSSA LOC101928548 LOC100130872 SPON2 CTBP1-AS NKX1-1 CTBP1-AS2 CRIPAK CTBP1
nsv593302	Chr.4:1344830 - 1420896 on Build GRCh38	Loss	UVSSA NKX1-1 CRIPAK
nsv950333	Chr.4:1400613 - 1419112 on Build GRCh38	Deletion	NKX1-1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

homeodomain transcription factor

Gene Ontology Categories:

Process(es)

regulation of transcription, DNA-templated
lipid metabolic process
biological_process
regulation of glucose metabolic process
regulation of generation of precursor metabolites and energy
neurological system process

Function(s)

sequence-specific DNA binding