Hs03537418_cn

• Gene Symbol: AFF1
• Assay Reference Genome Location: Chr.4:86938855 on build GRCh38
• Cytoband: 4q21.3

Target Gene Details

• Entrez Gene ID: 4299
• Gene Name: AF4/FMR2 family member 1
• Gene Aliases: AF4, MLLT2, PBM1
• Location: Chr.4:86935002-87141054 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
AFF1	NM_001166693.2			NP_001160165.1
	XM_005263007.3			XP_005263064.1
	XM_005263009.3			XP_005263066.1
	XM_005263013.3			XP_005263070.1
	XM_011531973.2			XP_011530275.1
	XM_017008215.1			XP_016863704.1
	AK296149.1
	AK300364.1
	BC017432.1
	DC340279.1
	L13743.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv508297	Chr.4:86857630 - 86947356 on Build GRCh38	Deletion	C4orf36 LOC100506746 AFF1
nsv594787	Chr.4:86300674 - 86967515 on Build GRCh38	Gain	MIR4452 MAPK10 SLC10A6 C4orf36 LOC100506746 PTPN13 AFF1
nsv1013308	Chr.4:86848541 - 86949016 on Build GRCh38	Gain	SLC10A6 C4orf36 LOC100506746 AFF1

More Information

Additional Information:

For this assay, SNP(s) [rs78219683] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

DNA-binding transcription factor

Gene Ontology Categories:

Process(es)

regulation of transcription, DNA-templated

Function(s)

transcription factor activity, sequence-specific DNA binding
protein binding