Hs03549366_cn

• Gene Symbol: IL7R
• Assay Reference Genome Location: Chr.5:35859567 on build GRCh38
• Cytoband: 5p13.2

Target Gene Details

• Entrez Gene ID: 3575
• Gene Name: interleukin 7 receptor
• Gene Aliases: CD127, CDW127, IL-7R-alpha, IL7RA, ILRA
• Location: Chr.5:35856875-35879603 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
IL7R	NM_002185.3			NP_002176.2
	NR_120485.1
	XM_005248299.3			XP_005248356.1
	AK301220.1
	AK315251.1
	BC020717.1
	BC067537.1			AAH67537.1
	BC067538.1			AAH67538.1
	BC067539.1			AAH67539.1
	BC067540.1			AAH67540.1
	BC069999.1			AAH69999.1
	CD703890.1
	FJ529208.1
	M29696.1			AAA59157.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv483069	Chr.5:35785417 - 35955982 on Build GRCh38	Gain	IL7R SPEF2 CAPSL LOC100506406 UGT3A1
esv3604707	Chr.5:35513484 - 36501574 on Build GRCh38	Gain	NADK2 IL7R SPEF2 CAPSL SKP2 UGT3A2 LOC100506406 LMBRD2 MIR580 UGT3A1 RANBP3L
esv3570069	Chr.5:35858977 - 35873099 on Build GRCh38	Loss	IL7R
nsv597813	Chr.5:35855162 - 35864488 on Build GRCh38	Gain	IL7R

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

regulation of DNA recombination
cell morphogenesis
negative regulation of T cell mediated cytotoxicity
immunoglobulin production
immune response
signal transduction
cell surface receptor signaling pathway
regulation of cell size
positive regulation of gene expression
cell growth
T cell differentiation
positive regulation of T cell differentiation in thymus
interleukin-7-mediated signaling pathway
B cell proliferation
lymph node development
homeostasis of number of cells

Function(s)

antigen binding
interleukin-7 receptor activity
protein binding